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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
PUF4
  • cytoplasm
  • loss of chromatin silencing involved in replicative cell aging
  • protein localization
  • mRNA catabolic process
  • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • mRNA binding
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL24A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL29
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL30
  • cytoplasm
  • negative regulation of nuclear mRNA splicing, via spliceosome
  • rRNA processing
  • negative regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL32
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL43B, RPL43A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • metal ion binding
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • YHI9
  • cellular_component
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 4.797E-21 17 101 13 6292
    cytosolic part 6.3752E-20 17 122 13 6292
    ribosomal subunit 1.4992E-17 17 183 13 6292
    cytosolic large ribosomal subunit 5.2374E-17 17 60 10 6292
    cytosol 4.9973E-15 17 284 13 6292
    ribosome 6.5721E-15 17 290 13 6292
    large ribosomal subunit 3.0952E-14 17 110 10 6292
    ribonucleoprotein complex 1.0968E-11 17 514 13 6292
    non-membrane-bounded organelle 2.9132E-8 17 959 13 6292
    intracellular non-membrane-bounded organelle 2.9132E-8 17 959 13 6292
    macromolecular complex 1.8944E-5 17 1635 13 6292
    cytosolic small ribosomal subunit 1.3039E-4 17 38 3 6292
    cytoplasm 8.3722E-4 17 3552 16 6292
    organelle part 8.5928E-4 17 2282 13 6292
    intracellular organelle part 8.5928E-4 17 2282 13 6292
    small ribosomal subunit 9.0665E-4 17 73 3 6292
    cytoplasmic part 2.1458E-3 17 2482 13 6292
    stress granule 2.7018E-3 17 1 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 4.1283E-17 17 376 15 6292
    cellular macromolecule biosynthetic process 3.3217E-11 17 1187 16 6292
    macromolecule biosynthetic process 3.4118E-11 17 1189 16 6292
    gene expression 1.1414E-10 17 1283 16 6292
    cellular protein metabolic process 2.7032E-10 17 1074 15 6292
    protein metabolic process 6.1691E-10 17 1136 15 6292
    cellular biosynthetic process 2.697E-9 17 1567 16 6292
    biosynthetic process 3.8206E-9 17 1602 16 6292
    cellular macromolecule metabolic process 9.9267E-7 17 2285 16 6292
    macromolecule metabolic process 1.5241E-6 17 2349 16 6292
    primary metabolic process 3.8308E-5 17 2896 16 6292
    cellular metabolic process 7.7499E-5 17 3033 16 6292
    metabolic process 1.4236E-4 17 3157 16 6292
    ribosomal subunit assembly 3.9412E-4 17 55 3 6292
    regulation of translation 4.381E-4 17 57 3 6292
    posttranscriptional regulation of gene expression 5.3527E-4 17 61 3 6292
    ribosome assembly 6.1656E-4 17 64 3 6292
    regulation of cellular protein metabolic process 7.3669E-4 17 68 3 6292
    organelle assembly 7.6889E-4 17 69 3 6292
    regulation of protein metabolic process 9.4338E-4 17 74 3 6292
    ribosome biogenesis 1.7448E-3 17 346 5 6292
    ribonucleoprotein complex assembly 1.7734E-3 17 92 3 6292
    ribosomal small subunit biogenesis 2.1497E-3 17 26 2 6292
    ribonucleoprotein complex biogenesis 2.4643E-3 17 374 5 6292
    response to cycloalkane 2.7018E-3 17 1 1 6292
    response to organic cyclic substance 2.7018E-3 17 1 1 6292
    negative regulation of mRNA processing 2.7018E-3 17 1 1 6292
    negative regulation of nuclear mRNA splicing, via spliceosome 2.7018E-3 17 1 1 6292
    negative regulation of RNA splicing 2.7018E-3 17 1 1 6292
    response to cycloheximide 2.7018E-3 17 1 1 6292
    ribosomal large subunit assembly 5.2962E-3 17 41 2 6292
    regulation of mRNA processing 5.3968E-3 17 2 1 6292
    regulation of RNA splicing 5.3968E-3 17 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 5.3968E-3 17 2 1 6292
    response to antibiotic 8.0849E-3 17 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 6.4251E-21 17 212 15 6292
    structural molecule activity 8.5585E-18 17 339 15 6292
    RNA binding 2.267E-3 17 367 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle