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Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism. The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cleavage. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA processing. Any cellular process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-end processing.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of mRNA processing
Acc: GO:0050686
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of mRNA processing.
Synonyms:
  • down-regulation of mRNA processing
  • downregulation of mRNA processing
  • down regulation of mRNA processing
  • inhibition of mRNA processing
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050686 - negative regulation of mRNA processing (interactive image map)

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