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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BRX1
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • 5S rRNA binding
  • rRNA primary transcript binding
  • CIC1
  • proteasome complex
  • nucleolus
  • protein catabolic process
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • protein binding, bridging
  • DBP9
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • HAS1
  • nuclear envelope
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • RNA-dependent ATPase activity
  • ATP-dependent RNA helicase activity
  • NIP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • molecular_function
  • NOG1
  • nuclear outer membrane
  • nucleolus
  • preribosome, large subunit precursor
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • GTP binding
  • NUG1
  • nucleus
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • GTPase activity
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • RPL1A, RPL1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • RNA processing
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL25
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleolus 5.963E-11 10 211 8 6292
    non-membrane-bounded organelle 6.5007E-9 10 959 10 6292
    intracellular non-membrane-bounded organelle 6.5007E-9 10 959 10 6292
    nuclear lumen 2.6926E-8 10 453 8 6292
    organelle lumen 5.2324E-7 10 660 8 6292
    intracellular organelle lumen 5.2324E-7 10 660 8 6292
    membrane-enclosed lumen 8.2941E-7 10 700 8 6292
    nuclear part 2.8079E-5 10 1103 8 6292
    organelle part 3.8887E-5 10 2282 10 6292
    intracellular organelle part 3.8887E-5 10 2282 10 6292
    nucleus 2.7794E-3 10 2041 8 6292
    nuclear envelope 3.1727E-3 10 199 3 6292
    cytosolic large ribosomal subunit 3.8312E-3 10 60 2 6292
    nuclear outer membrane 7.7386E-3 10 86 2 6292
    nuclear membrane 9.7663E-3 10 97 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit biogenesis 1.0561E-12 10 65 7 6292
    ribosome biogenesis 3.963E-11 10 346 9 6292
    ribonucleoprotein complex biogenesis 8.0128E-11 10 374 9 6292
    cellular component biogenesis 2.0804E-8 10 694 9 6292
    ribosomal large subunit assembly 3.1687E-7 10 41 4 6292
    ribosomal subunit assembly 1.0557E-6 10 55 4 6292
    ribosome assembly 1.9533E-6 10 64 4 6292
    organelle assembly 2.6475E-6 10 69 4 6292
    ribonucleoprotein complex assembly 8.4067E-6 10 92 4 6292
    cellular macromolecular complex assembly 1.2411E-4 10 182 4 6292
    cellular macromolecular complex subunit organization 4.8407E-4 10 259 4 6292
    macromolecular complex assembly 6.6045E-4 10 281 4 6292
    rRNA processing 8.8893E-4 10 128 3 6292
    rRNA metabolic process 1.0834E-3 10 137 3 6292
    macromolecular complex subunit organization 1.628E-3 10 357 4 6292
    RNA processing 2.0543E-3 10 380 4 6292
    cellular component assembly 2.1564E-3 10 385 4 6292
    ncRNA processing 3.9518E-3 10 215 3 6292
    ncRNA metabolic process 6.5282E-3 10 257 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA binding 1.2975E-4 10 367 5 6292
    rRNA binding 2.6962E-4 10 16 2 6292
    ATP-dependent RNA helicase activity 8.4071E-4 10 28 2 6292
    RNA-dependent ATPase activity 9.0222E-4 10 29 2 6292
    binding 1.0216E-3 10 1294 7 6292
    RNA helicase activity 1.8923E-3 10 42 2 6292
    nucleic acid binding 2.094E-3 10 666 5 6292
    ATP-dependent helicase activity 2.4666E-3 10 48 2 6292
    purine NTP-dependent helicase activity 2.4666E-3 10 48 2 6292
    5S rRNA binding 3.1764E-3 10 2 1 6292
    helicase activity 7.2234E-3 10 83 2 6292
    rRNA primary transcript binding 7.9239E-3 10 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle