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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • PNO1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • protein complex assembly
  • ribosome biogenesis
  • rRNA processing
  • unfolded protein binding
  • RRP12
  • nucleus
  • ribosome
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP8
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 5.6097E-18 13 72 10 6292
    nuclear outer membrane 7.427E-15 13 86 9 6292
    nuclear membrane 2.2935E-14 13 97 9 6292
    ribonucleoprotein complex 9.4432E-13 13 514 12 6292
    outer membrane 6.1609E-12 13 178 9 6292
    organelle outer membrane 6.1609E-12 13 178 9 6292
    nuclear envelope 1.6972E-11 13 199 9 6292
    nucleolus 2.8849E-11 13 211 9 6292
    nuclear membrane-endoplasmic reticulum network 6.7995E-11 13 232 9 6292
    endomembrane system 8.4634E-9 13 398 9 6292
    nuclear lumen 2.6533E-8 13 453 9 6292
    envelope 6.891E-8 13 505 9 6292
    organelle envelope 6.891E-8 13 505 9 6292
    organelle lumen 7.0793E-7 13 660 9 6292
    intracellular organelle lumen 7.0793E-7 13 660 9 6292
    membrane part 7.2667E-7 13 662 9 6292
    macromolecular complex 9.1057E-7 13 1635 12 6292
    organelle membrane 1.0651E-6 13 692 9 6292
    membrane-enclosed lumen 1.1759E-6 13 700 9 6292
    non-membrane-bounded organelle 1.1943E-6 13 959 10 6292
    intracellular non-membrane-bounded organelle 1.1943E-6 13 959 10 6292
    nuclear part 4.5247E-6 13 1103 10 6292
    preribosome 3.9744E-5 13 34 3 6292
    preribosome, small subunit precursor 5.8841E-5 13 6 2 6292
    membrane 1.09E-4 13 1198 9 6292
    nucleus 1.5889E-4 13 2041 11 6292
    intracellular organelle part 3.3831E-3 13 2282 10 6292
    organelle part 3.3831E-3 13 2282 10 6292
    nucleolar part 3.7109E-3 13 45 2 6292
    Noc4p-Nop14p complex 4.1283E-3 13 2 1 6292
    RENT complex 8.2408E-3 13 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA processing 1.2068E-17 13 128 11 6292
    rRNA metabolic process 2.6184E-17 13 137 11 6292
    ribosome biogenesis 3.3886E-17 13 346 13 6292
    ribonucleoprotein complex biogenesis 9.4812E-17 13 374 13 6292
    ncRNA processing 4.2348E-15 13 215 11 6292
    ncRNA metabolic process 3.1081E-14 13 257 11 6292
    maturation of SSU-rRNA 4.5379E-14 13 59 8 6292
    cellular component biogenesis 3.2337E-13 13 694 13 6292
    RNA processing 2.3731E-12 13 380 11 6292
    RNA metabolic process 5.3775E-8 13 954 11 6292
    gene expression 1.2671E-6 13 1283 11 6292
    nucleic acid metabolic process 3.5616E-6 13 1415 11 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.0311E-5 13 1566 11 6292
    cellular nitrogen compound metabolic process 3.6818E-5 13 1770 11 6292
    nitrogen compound metabolic process 4.1589E-5 13 1791 11 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.0349E-4 13 13 2 6292
    cellular macromolecule metabolic process 4.9766E-4 13 2285 11 6292
    macromolecule metabolic process 6.5617E-4 13 2349 11 6292
    ribosomal small subunit biogenesis 1.2455E-3 13 26 2 6292
    primary metabolic process 5.1003E-3 13 2896 11 6292
    ncRNA 5'-end processing 6.1865E-3 13 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.1865E-3 13 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.1865E-3 13 3 1 6292
    rRNA 5'-end processing 6.1865E-3 13 3 1 6292
    RNA 5'-end processing 6.1865E-3 13 3 1 6292
    cellular metabolic process 7.9165E-3 13 3033 11 6292
    maturation of 5.8S rRNA 8.2408E-3 13 4 1 6292
    cleavage involved in rRNA processing 8.2408E-3 13 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.2408E-3 13 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.2408E-3 13 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 8.2408E-3 13 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.2408E-3 13 4 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 5.7285E-14 13 31 7 6292
    RNA binding 2.7439E-6 13 367 7 6292
    nucleic acid binding 1.3972E-4 13 666 7 6292
    binding 1.4925E-3 13 1294 8 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle