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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BFR2
  • nucleolus
  • ER to Golgi vesicle-mediated transport
  • molecular_function
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ROK1
  • nuclear outer membrane
  • nucleolus
  • snoRNA localization
  • ribosome biogenesis
  • rRNA processing
  • ATPase activity
  • ATP-dependent RNA helicase activity
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP21
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 3.8452E-15 14 72 9 6292
    nucleolus 1.5546E-14 14 211 11 6292
    nuclear outer membrane 2.0566E-14 14 86 9 6292
    nuclear membrane 6.3408E-14 14 97 9 6292
    outer membrane 1.6833E-11 14 178 9 6292
    organelle outer membrane 1.6833E-11 14 178 9 6292
    nuclear envelope 4.6229E-11 14 199 9 6292
    nuclear lumen 7.1666E-11 14 453 11 6292
    nuclear membrane-endoplasmic reticulum network 1.8431E-10 14 232 9 6292
    nuclear part 1.6352E-9 14 1103 13 6292
    organelle lumen 4.2389E-9 14 660 11 6292
    intracellular organelle lumen 4.2389E-9 14 660 11 6292
    membrane-enclosed lumen 7.9804E-9 14 700 11 6292
    endomembrane system 2.238E-8 14 398 9 6292
    envelope 1.7927E-7 14 505 9 6292
    organelle envelope 1.7927E-7 14 505 9 6292
    ribonucleoprotein complex 2.0898E-7 14 514 9 6292
    non-membrane-bounded organelle 2.2878E-7 14 959 11 6292
    intracellular non-membrane-bounded organelle 2.2878E-7 14 959 11 6292
    membrane part 1.8451E-6 14 662 9 6292
    organelle membrane 2.6916E-6 14 692 9 6292
    nucleus 4.2048E-6 14 2041 13 6292
    intracellular organelle part 1.7098E-5 14 2282 13 6292
    organelle part 1.7098E-5 14 2282 13 6292
    preribosome 5.0397E-5 14 34 3 6292
    small-subunit processome 6.8619E-5 14 6 2 6292
    membrane 2.5364E-4 14 1198 9 6292
    macromolecular complex 2.8523E-3 14 1635 9 6292
    nucleolar part 4.3098E-3 14 45 2 6292
    Noc4p-Nop14p complex 4.4455E-3 14 2 1 6292
    membrane-bounded organelle 7.9402E-3 14 3771 13 6292
    intracellular membrane-bounded organelle 7.9402E-3 14 3771 13 6292
    RENT complex 8.8726E-3 14 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 4.5104E-16 14 346 13 6292
    ribonucleoprotein complex biogenesis 1.2565E-15 14 374 13 6292
    cellular component biogenesis 4.0713E-12 14 694 13 6292
    rRNA processing 6.3877E-11 14 128 8 6292
    rRNA metabolic process 1.108E-10 14 137 8 6292
    ncRNA processing 4.1121E-9 14 215 8 6292
    ncRNA metabolic process 1.6885E-8 14 257 8 6292
    maturation of SSU-rRNA 1.1451E-7 14 59 5 6292
    RNA processing 3.5858E-7 14 380 8 6292
    RNA metabolic process 3.4699E-4 14 954 8 6292
    ribosomal small subunit biogenesis 1.4494E-3 14 26 2 6292
    snoRNA localization 2.225E-3 14 1 1 6292
    gene expression 2.6989E-3 14 1283 8 6292
    nucleic acid metabolic process 5.169E-3 14 1415 8 6292
    ncRNA 5'-end processing 6.6614E-3 14 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.6614E-3 14 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.6614E-3 14 3 1 6292
    rRNA 5'-end processing 6.6614E-3 14 3 1 6292
    RNA 5'-end processing 6.6614E-3 14 3 1 6292
    cellular process 7.2188E-3 14 4426 14 6292
    maturation of 5.8S rRNA 8.8726E-3 14 4 1 6292
    cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.9462E-3 14 1566 8 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 2.5025E-11 14 31 6 6292
    RNA binding 7.6075E-5 14 367 6 6292
    nucleic acid binding 1.9573E-3 14 666 6 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle