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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BFR2
  • nucleolus
  • ER to Golgi vesicle-mediated transport
  • molecular_function
  • BMS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • nuclear outer membrane
  • nucleolus
  • ribosome assembly
  • rRNA processing
  • GTP binding
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • ENP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleolus 9.2374E-19 17 211 14 6292
    small nucleolar ribonucleoprotein complex 2.3329E-18 17 72 11 6292
    nuclear outer membrane 1.8651E-17 17 86 11 6292
    nuclear membrane 7.5098E-17 17 97 11 6292
    nuclear lumen 4.6247E-14 17 453 14 6292
    outer membrane 7.2966E-14 17 178 11 6292
    organelle outer membrane 7.2966E-14 17 178 11 6292
    nuclear envelope 2.5258E-13 17 199 11 6292
    nuclear membrane-endoplasmic reticulum network 1.3807E-12 17 232 11 6292
    organelle lumen 8.661E-12 17 660 14 6292
    intracellular organelle lumen 8.661E-12 17 660 14 6292
    nuclear part 1.0341E-11 17 1103 16 6292
    membrane-enclosed lumen 1.9508E-11 17 700 14 6292
    ribonucleoprotein complex 3.3089E-10 17 514 12 6292
    endomembrane system 4.9714E-10 17 398 11 6292
    non-membrane-bounded organelle 1.4544E-9 17 959 14 6292
    intracellular non-membrane-bounded organelle 1.4544E-9 17 959 14 6292
    envelope 6.3606E-9 17 505 11 6292
    organelle envelope 6.3606E-9 17 505 11 6292
    preribosome 2.0038E-8 17 34 5 6292
    membrane part 1.1044E-7 17 662 11 6292
    nucleus 1.7093E-7 17 2041 16 6292
    organelle membrane 1.7533E-7 17 692 11 6292
    preribosome, small subunit precursor 3.261E-7 17 6 3 6292
    intracellular organelle part 9.7262E-7 17 2282 16 6292
    organelle part 9.7262E-7 17 2282 16 6292
    Noc4p-Nop14p complex 6.8716E-6 17 2 2 6292
    membrane 4.5594E-5 17 1198 11 6292
    Noc complex 6.8389E-5 17 5 2 6292
    small-subunit processome 1.0242E-4 17 6 2 6292
    macromolecular complex 1.4652E-4 17 1635 12 6292
    nucleolar part 2.1677E-4 17 45 3 6292
    90S preribosome 9.1252E-4 17 17 2 6292
    membrane-bounded organelle 2.0321E-3 17 3771 16 6292
    intracellular membrane-bounded organelle 2.0321E-3 17 3771 16 6292
    intracellular organelle 6.1965E-3 17 4070 16 6292
    organelle 6.2185E-3 17 4071 16 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 8.0979E-20 17 346 16 6292
    ribonucleoprotein complex biogenesis 2.876E-19 17 374 16 6292
    rRNA processing 1.6938E-17 17 128 12 6292
    rRNA metabolic process 3.9417E-17 17 137 12 6292
    cellular component biogenesis 6.2754E-15 17 694 16 6292
    ncRNA processing 9.9625E-15 17 215 12 6292
    ncRNA metabolic process 8.6493E-14 17 257 12 6292
    maturation of SSU-rRNA 8.3269E-13 17 59 8 6292
    RNA processing 9.3571E-12 17 380 12 6292
    RNA metabolic process 4.0927E-7 17 954 12 6292
    gene expression 1.0943E-5 17 1283 12 6292
    nucleic acid metabolic process 3.1589E-5 17 1415 12 6292
    ribosomal small subunit biogenesis 4.1E-5 17 26 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.3083E-5 17 1566 12 6292
    cellular nitrogen compound metabolic process 3.3419E-4 17 1770 12 6292
    nitrogen compound metabolic process 3.7731E-4 17 1791 12 6292
    rRNA modification 1.0249E-3 17 18 2 6292
    cellular process 2.5051E-3 17 4426 17 6292
    cellular macromolecule metabolic process 4.2495E-3 17 2285 12 6292
    macromolecule metabolic process 5.5253E-3 17 2349 12 6292
    ncRNA 5'-end processing 8.0849E-3 17 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.0849E-3 17 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.0849E-3 17 3 1 6292
    rRNA 5'-end processing 8.0849E-3 17 3 1 6292
    RNA 5'-end processing 8.0849E-3 17 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 6.4059E-13 17 31 7 6292
    RNA binding 2.5345E-5 17 367 7 6292
    nucleic acid binding 1.0827E-3 17 666 7 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle