From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.509373269906] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear chromatin | 1.3278E-4 | 2 | 73 | 2 | 6292 |
chromatin | 1.4784E-4 | 2 | 77 | 2 | 6292 |
FACT complex | 6.3568E-4 | 2 | 2 | 1 | 6292 |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
nucleoplasm part | 1.5102E-3 | 2 | 245 | 2 | 6292 |
nucleoplasm | 1.7541E-3 | 2 | 264 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
alpha DNA polymerase:primase complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
Ino80 complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
DNA helicase complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
NuA4 histone acetyltransferase complex | 4.4455E-3 | 2 | 14 | 1 | 6292 |
H4/H2A histone acetyltransferase complex | 4.4455E-3 | 2 | 14 | 1 | 6292 |
Swr1 complex | 4.7627E-3 | 2 | 15 | 1 | 6292 |
nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
nuclear replisome | 5.7138E-3 | 2 | 18 | 1 | 6292 |
replisome | 5.7138E-3 | 2 | 18 | 1 | 6292 |
nuclear replication fork | 6.3477E-3 | 2 | 20 | 1 | 6292 |
transcription elongation factor complex | 7.2981E-3 | 2 | 23 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
chromatin remodeling | 1.151E-4 | 2 | 68 | 2 | 6292 |
chromatin modification | 7.0879E-4 | 2 | 168 | 2 | 6292 |
chromatin organization | 1.036E-3 | 2 | 203 | 2 | 6292 |
transcription from RNA polymerase II promoter | 2.8267E-3 | 2 | 335 | 2 | 6292 |
transcription, DNA-dependent | 6.3792E-3 | 2 | 503 | 2 | 6292 |
RNA biosynthetic process | 6.5067E-3 | 2 | 508 | 2 | 6292 |
transcription | 7.6839E-3 | 2 | 552 | 2 | 6292 |
chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
chromatin binding | 2.6678E-5 | 2 | 33 | 2 | 6292 |
ATP-dependent 5'-3' DNA helicase activity | 2.224E-3 | 2 | 7 | 1 | 6292 |
5'-3' DNA helicase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
histone acetyltransferase activity | 5.3968E-3 | 2 | 17 | 1 | 6292 |
lysine N-acetyltransferase activity | 5.3968E-3 | 2 | 17 | 1 | 6292 |
ATP-dependent DNA helicase activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |