From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.084] [SVM Score: 0.511763250735] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
replication fork | 4.3504E-5 | 2 | 42 | 2 | 6292 |
protein-DNA complex | 8.0641E-5 | 2 | 57 | 2 | 6292 |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
MCM complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
alpha DNA polymerase:primase complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
pre-replicative complex | 5.0798E-3 | 2 | 16 | 1 | 6292 |
nuclear replisome | 5.7138E-3 | 2 | 18 | 1 | 6292 |
replisome | 5.7138E-3 | 2 | 18 | 1 | 6292 |
nuclear replication fork | 6.3477E-3 | 2 | 20 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA replication initiation | 2.6678E-5 | 2 | 33 | 2 | 6292 |
DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
establishment of chromatin silencing | 9.5344E-4 | 2 | 3 | 1 | 6292 |
DNA synthesis involved in DNA repair | 1.2712E-3 | 2 | 4 | 1 | 6292 |
DNA replication, synthesis of RNA primer | 1.5888E-3 | 2 | 5 | 1 | 6292 |
pre-replicative complex assembly | 4.1283E-3 | 2 | 13 | 1 | 6292 |
DNA unwinding involved in replication | 4.4455E-3 | 2 | 14 | 1 | 6292 |
lagging strand elongation | 5.7138E-3 | 2 | 18 | 1 | 6292 |
DNA geometric change | 6.3477E-3 | 2 | 20 | 1 | 6292 |
DNA duplex unwinding | 6.3477E-3 | 2 | 20 | 1 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
DNA strand elongation | 9.8303E-3 | 2 | 31 | 1 | 6292 |
DNA strand elongation involved in DNA replication | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA primase activity | 6.3568E-4 | 2 | 2 | 1 | 6292 |
ATP-dependent DNA helicase activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |