Protein Overview: FIN1

General Information:
Name(s) found:	FIN1 / YDR130C [SGD]
Description(s) found: Found 29 descriptions. SHOW ALL	Spindle pole body-related intermediate filament protein; forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells; localization cell-cycle dependent; involved in Glc7p localization and regulation [SGD]
Organism:	Saccharomyces cerevisiae
Length:	291 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA ] spindle pole body [IDA ] spindle [IDA ][IMP] intermediate filament [IDA] astral microtubule [IDA]
Biological Process:	mitotic sister chromatid segregation [IMP] intermediate filament-based process [IDA] mitotic spindle stabilization [IMP]
Molecular Function:	structural constituent of cytoskeleton [IDA] microtubule binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKSNRRSL RDIGNTIGRN NIPSDKDNVF VRLSMSPLRT TSQKEFLKPP MRISPNKTDG  60
   61 MKHSIQVTPR RIMSPECLKG YVSKETQSLD RPQFKNSNKN VKIQNSDHIT NIIFPTSPTK 120
  121 LTFSNENKIG GDGSLTRIRA RFKNGLMSPE RIQQQQQQHI LPSDAKSNTD LCSNTELKDA 180
  181 PFENDLPRAK LKGKNLLVEL KKEEEDVGNG IESLTKSNTK LNSMLANEGK IHKASFQKSV 240
  241 KFKLPDNIVT EETVELKEIK DLLLQMLRRQ REIESRLSNI ELQLTEIPKH K

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		CFT1 CIC1 CLU1 ERB1 FIN1 FIP1 FPR3 FPR4 GLC7 GLC8 GPH1 GSY1 HER1 KEL1 MHP1 NOP7 NSA1 REG1 RRP17 SCD5 SDS22 SEN1 SPB1 SUI2 SUI3 YTM1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)
View Run	MLP2	#25 Asynchronous Prep3-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	FIN1	NFI1	2	Unpublished Fields Lab Data
View Screen	GLC7	FIN1	2	Uetz P, et al. (2000)
View Screen	CLB5	FIN1	2	Unpublished Fields Lab Data
View Screen	CDC28	FIN1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	FIN1 and SPC42	Huh WK, et al. (2003)
View Data	FIN1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..291]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2