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Any process involved in maintaining the structure and integrity of the spindle. Any process that modulates the rate or extent of progress through the mitotic cell cycle. Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle. The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. The cell cycle process whereby spindle integrity is maintained during M phase of mitosis. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mitotic spindle stabilization
Acc: GO:0043148
Aspect: Biological Process
Desc: The cell cycle process whereby spindle integrity is maintained during M phase of mitosis.
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043148 - mitotic spindle stabilization (interactive image map)
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Created and Maintained by: Michael Riffle