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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
HCA4
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ATP-dependent RNA helicase activity
  • IML1
  • fungal-type vacuole membrane
  • biological_process
  • molecular_function
  • LHP1
  • nucleus
  • nucleolus
  • nucleoplasm
  • tRNA processing
  • RNA binding
  • NAB3
  • nucleus
  • termination of RNA polymerase II transcription, poly(A)-independent
  • regulation of transcription from RNA polymerase II promoter
  • poly(A) RNA binding
  • NAB6
  • cytoplasm
  • RNA metabolic process
  • molecular_function
  • NAM7
  • polysome
  • cytoplasm
  • mitochondrion
  • regulation of translational termination
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • telomere maintenance
  • translational frameshifting
  • mRNA catabolic process
  • chromatin silencing at silent mating-type cassette
  • nucleic acid binding
  • RNA-dependent ATPase activity
  • ATP-dependent RNA helicase activity
  • NPL3
  • nucleus
  • cytoplasm
  • mRNA export from nucleus
  • pseudohyphal growth
  • poly(A) RNA binding
  • mRNA binding
  • NRD1
  • nuclear exosome (RNase complex)
  • nucleus
  • termination of RNA polymerase II transcription, poly(A)-independent
  • RNA binding
  • NRP1
  • cytoplasm
  • ribosome biogenesis
  • molecular_function
  • POL2
  • replication fork
  • epsilon DNA polymerase complex
  • lagging strand elongation
  • leading strand elongation
  • nucleotide-excision repair
  • mismatch repair
  • DNA synthesis involved in DNA repair
  • chromatin silencing at telomere
  • nucleotide binding
  • nucleic acid binding
  • DNA binding
  • zinc ion binding
  • DNA-directed DNA polymerase activity
  • nucleotidyltransferase activity
  • metal ion binding
  • double-stranded DNA binding
  • transferase activity
  • PUB1
  • nucleus
  • cytoplasm
  • heterogeneous nuclear ribonucleoprotein complex
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • regulation of mRNA stability
  • nucleic acid binding
  • mRNA binding
  • SGN1
  • cytoplasm
  • mRNA metabolic process
  • poly(A) RNA binding
  • SMD3
  • commitment complex
  • U4/U6 x U5 tri-snRNP complex
  • U5 snRNP
  • U1 snRNP
  • nuclear mRNA splicing, via spliceosome
  • mRNA binding
  • SNF2
  • SWI/SNF complex
  • chromatin remodeling complex
  • chromatin remodeling
  • double-strand break repair
  • DNA-dependent ATPase activity
  • general RNA polymerase II transcription factor activity
  • STO1
  • commitment complex
  • nuclear cap binding complex
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • telomere maintenance
  • nuclear mRNA splicing, via spliceosome
  • mRNA binding
  • SWI1
  • SWI/SNF complex
  • chromatin remodeling complex
  • chromatin remodeling
  • regulation of transcription from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TIF4631
  • eukaryotic translation initiation factor 4F complex
  • mitochondrion
  • ribosome
  • ribosome biogenesis
  • translational initiation
  • translation initiation factor activity
  • TIF4632
  • eukaryotic translation initiation factor 4F complex
  • ribosome
  • translational initiation
  • translation initiation factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    eukaryotic translation initiation factor 4F complex 4.6226E-5 18 4 2 6292
    U2-type spliceosomal complex 5.0164E-4 18 12 2 6292
    commitment complex 5.0164E-4 18 12 2 6292
    SWI/SNF-type complex 5.9184E-4 18 13 2 6292
    SWI/SNF complex 5.9184E-4 18 13 2 6292
    nuclear part 1.6158E-3 18 1103 9 6292
    ribonucleoprotein complex 2.2861E-3 18 514 6 6292
    spliceosomal complex 7.1157E-3 18 45 2 6292
    macromolecular complex 7.2099E-3 18 1635 10 6292
    heterogeneous nuclear ribonucleoprotein complex 8.5592E-3 18 3 1 6292
    nuclear cap binding complex 8.5592E-3 18 3 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3.1985E-6 18 11 3 6292
    RNA metabolic process 1.0499E-5 18 954 11 6292
    nucleic acid metabolic process 7.5372E-5 18 1415 12 6292
    nuclear-transcribed mRNA catabolic process 1.5581E-4 18 38 3 6292
    cellular protein complex disassembly 1.6849E-4 18 39 3 6292
    protein complex disassembly 1.6849E-4 18 39 3 6292
    cellular macromolecular complex disassembly 1.8183E-4 18 40 3 6292
    macromolecular complex disassembly 1.8183E-4 18 40 3 6292
    gene expression 1.8647E-4 18 1283 11 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.1602E-4 18 1566 12 6292
    cellular component disassembly 2.42E-4 18 44 3 6292
    mRNA metabolic process 2.534E-4 18 213 5 6292
    termination of RNA polymerase II transcription, poly(A)-independent 2.7502E-4 18 9 2 6292
    cellular macromolecule metabolic process 4.0124E-4 18 2285 14 6292
    macromolecule metabolic process 5.5843E-4 18 2349 14 6292
    cellular nitrogen compound metabolic process 7.4623E-4 18 1770 12 6292
    nitrogen compound metabolic process 8.3912E-4 18 1791 12 6292
    mRNA catabolic process 9.1545E-4 18 69 3 6292
    termination of RNA polymerase II transcription 1.2844E-3 18 19 2 6292
    RNA catabolic process 1.4075E-3 18 80 3 6292
    transcription termination 1.572E-3 18 21 2 6292
    regulation of RNA metabolic process 2.8506E-3 18 363 5 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.0929E-3 18 415 5 6292
    regulation of nitrogen compound metabolic process 5.1457E-3 18 416 5 6292
    translational initiation 6.2199E-3 18 42 2 6292
    primary metabolic process 6.241E-3 18 2896 14 6292
    regulation of gene expression 6.8545E-3 18 445 5 6292
    regulation of translational termination 8.5592E-3 18 3 1 6292
    regulation of mRNA stability 8.5592E-3 18 3 1 6292
    regulation of RNA stability 8.5592E-3 18 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA binding 3.3421E-10 18 35 6 6292
    nucleic acid binding 1.833E-8 18 666 12 6292
    poly(A) RNA binding 1.9594E-7 18 5 3 6292
    single-stranded RNA binding 1.9594E-7 18 5 3 6292
    poly-purine tract binding 1.9594E-7 18 5 3 6292
    RNA binding 3.2425E-6 18 367 8 6292
    binding 2.9285E-5 18 1294 12 6292
    translation initiation factor activity 2.6008E-3 18 27 2 6292
    ATP-dependent RNA helicase activity 2.7962E-3 18 28 2 6292
    RNA-dependent ATPase activity 2.9982E-3 18 29 2 6292
    RNA helicase activity 6.2199E-3 18 42 2 6292
    translation factor activity, nucleic acid binding 6.8109E-3 18 44 2 6292
    ATP-dependent helicase activity 8.0666E-3 18 48 2 6292
    purine NTP-dependent helicase activity 8.0666E-3 18 48 2 6292
    ATPase activity, coupled 8.1798E-3 18 149 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle