YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 6 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC55
  • nucleus
  • cellular bud tip
  • cellular bud neck
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • negative regulation of exit from mitosis
  • protein amino acid dephosphorylation
  • pseudohyphal growth
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • PPH21
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • PPH22
  • condensed nuclear chromosome, centromeric region
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • RTS1
  • nucleus
  • condensed nuclear chromosome, centromeric region
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • protein phosphatase type 2A complex
  • protein amino acid dephosphorylation
  • meiotic sister chromatid cohesion, centromeric
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • TPD3
  • nucleus
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • mating projection tip
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • ZDS1
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • nuclear pore
  • mRNA export from nucleus
  • chromatin silencing
  • cell aging
  • protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 2A complex 4.3871E-16 6 6 5 6292
    protein serine/threonine phosphatase complex 4.5179E-13 6 17 5 6292
    cellular bud neck 2.4513E-6 6 129 4 6292
    cellular bud 6.7281E-6 6 166 4 6292
    site of polarized growth 7.0577E-6 6 168 4 6292
    cellular bud tip 1.3832E-5 6 57 3 6292
    protein complex 3.4445E-5 6 1137 6 6292
    macromolecular complex 3.0579E-4 6 1635 6 6292
    condensed chromosome, centromeric region 1.1004E-3 6 55 2 6292
    condensed nuclear chromosome, centromeric region 1.1004E-3 6 55 2 6292
    microtubule organizing center 1.4423E-3 6 63 2 6292
    spindle pole body 1.4423E-3 6 63 2 6292
    chromosome, centromeric region 1.6301E-3 6 67 2 6292
    spindle pole 1.6787E-3 6 68 2 6292
    condensed nuclear chromosome 2.6729E-3 6 86 2 6292
    spindle 2.8601E-3 6 89 2 6292
    condensed chromosome 3.1857E-3 6 94 2 6292
    microtubule cytoskeleton 4.0352E-3 6 106 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein amino acid dephosphorylation 7.165E-12 6 28 5 6292
    dephosphorylation 4.7895E-11 6 40 5 6292
    mitotic cell cycle spindle assembly checkpoint 1.3701E-9 6 21 4 6292
    negative regulation of nuclear division 1.3701E-9 6 21 4 6292
    negative regulation of mitosis 1.3701E-9 6 21 4 6292
    negative regulation of mitotic metaphase/anaphase transition 1.3701E-9 6 21 4 6292
    spindle assembly checkpoint 1.3701E-9 6 21 4 6292
    negative regulation of cell cycle 1.6741E-9 6 22 4 6292
    spindle checkpoint 2.8929E-9 6 25 4 6292
    regulation of mitotic metaphase/anaphase transition 2.8929E-9 6 25 4 6292
    mitotic cell cycle spindle checkpoint 2.8929E-9 6 25 4 6292
    mitotic cell cycle checkpoint 4.6787E-9 6 28 4 6292
    negative regulation of cellular component organization 5.426E-9 6 29 4 6292
    regulation of nuclear division 5.426E-9 6 29 4 6292
    negative regulation of organelle organization 5.426E-9 6 29 4 6292
    regulation of mitosis 5.426E-9 6 29 4 6292
    negative regulation of cell cycle process 8.2088E-9 6 32 4 6292
    budding cell bud growth 1.0581E-8 6 34 4 6292
    mitotic metaphase/anaphase transition 1.5057E-8 6 37 4 6292
    regulation of organelle organization 6.1485E-8 6 52 4 6292
    cell cycle checkpoint 9.6209E-8 6 58 4 6292
    actin filament organization 1.842E-7 6 68 4 6292
    regulation of mitotic cell cycle 2.196E-7 6 71 4 6292
    regulation of cellular component organization 2.7442E-7 6 75 4 6292
    phosphorus metabolic process 3.5637E-7 6 229 5 6292
    phosphate metabolic process 3.5637E-7 6 229 5 6292
    regulation of cell cycle process 3.7506E-7 6 81 4 6292
    negative regulation of cellular process 5.5307E-7 6 250 5 6292
    cell budding 5.7469E-7 6 90 4 6292
    asexual reproduction 5.7469E-7 6 90 4 6292
    negative regulation of biological process 5.8711E-7 6 253 5 6292
    mitosis 1.0304E-6 6 104 4 6292
    nuclear division 1.1127E-6 6 106 4 6292
    M phase 1.244E-6 6 294 5 6292
    organelle fission 1.4396E-6 6 113 4 6292
    actin cytoskeleton organization 1.4396E-6 6 113 4 6292
    actin filament-based process 1.6559E-6 6 117 4 6292
    M phase of mitotic cell cycle 2.3759E-6 6 128 4 6292
    regulation of cell cycle 2.6075E-6 6 131 4 6292
    post-translational protein modification 3.2755E-6 6 357 5 6292
    growth 3.9173E-6 6 145 4 6292
    cell division 3.9173E-6 6 145 4 6292
    cell cycle phase 4.2398E-6 6 376 5 6292
    translation 4.2398E-6 6 376 5 6292
    cell cycle process 1.5781E-5 6 490 5 6292
    protein modification process 1.7269E-5 6 499 5 6292
    signal transduction 1.8503E-5 6 214 4 6292
    signal transmission 1.9555E-5 6 217 4 6292
    signaling process 1.9555E-5 6 217 4 6292
    reproduction of a single-celled organism 1.9555E-5 6 217 4 6292
    cell cycle 2.2202E-5 6 525 5 6292
    cytoskeleton organization 2.5062E-5 6 231 4 6292
    macromolecule modification 3.3042E-5 6 569 5 6292
    signaling 3.5378E-5 6 252 4 6292
    mitotic cell cycle 3.7074E-5 6 255 4 6292
    cellular macromolecule biosynthetic process 4.4618E-5 6 1187 6 6292
    macromolecule biosynthetic process 4.5072E-5 6 1189 6 6292
    gene expression 7.1216E-5 6 1283 6 6292
    reproduction 1.0008E-4 6 328 4 6292
    regulation of cellular process 1.7215E-4 6 796 5 6292
    regulation of biological process 2.0387E-4 6 824 5 6292
    cellular biosynthetic process 2.3689E-4 6 1567 6 6292
    biosynthetic process 2.7052E-4 6 1602 6 6292
    cellular protein metabolic process 7.4048E-4 6 1074 5 6292
    G1/S transition of mitotic cell cycle 9.0969E-4 6 50 2 6292
    organelle organization 9.3483E-4 6 1127 5 6292
    meiotic sister chromatid cohesion, centromeric 9.5359E-4 6 1 1 6292
    protein metabolic process 9.7146E-4 6 1136 5 6292
    biological regulation 1.333E-3 6 1213 5 6292
    meiotic sister chromatid cohesion 1.9064E-3 6 2 1 6292
    cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
    macromolecule metabolic process 2.6967E-3 6 2349 6 6292
    interphase of mitotic cell cycle 3.389E-3 6 97 2 6292
    interphase 3.389E-3 6 97 2 6292
    negative regulation of exit from mitosis 3.8098E-3 6 4 1 6292
    cellular component organization 4.7462E-3 6 1582 5 6292
    primary metabolic process 9.4808E-3 6 2896 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein serine/threonine phosphatase activity 3.418E-9 6 26 4 6292
    phosphoprotein phosphatase activity 2.8093E-8 6 43 4 6292
    phosphatase activity 5.0101E-7 6 87 4 6292
    phosphoric ester hydrolase activity 9.5282E-7 6 102 4 6292
    protein phosphatase type 2A regulator activity 4.5436E-6 6 4 2 6292
    hydrolase activity, acting on ester bonds 1.1659E-4 6 341 4 6292
    phosphatase regulator activity 1.9005E-4 6 23 2 6292
    protein phosphatase regulator activity 1.9005E-4 6 23 2 6292
    metal ion binding 1.1004E-3 6 55 2 6292
    ion binding 1.1407E-3 6 56 2 6292
    cation binding 1.1407E-3 6 56 2 6292
    hydrolase activity 5.1329E-3 6 911 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle