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A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p. A region of heterochromatin located near the centromere of a chromosome. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it. The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it. The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: chromosome, centromeric region
Acc: GO:0000775
Aspect: Cellular Component
Desc: The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
Synonyms:
  • centromere
  • chromosome, pericentric region
  • chromosome, centric region
Proteins in PDR annotated with:
   This term: 141 [Search]
   Term or descendants: 498 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000775 - chromosome, centromeric region (interactive image map)

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