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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CFT1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mitochondrion
  • mRNA cleavage factor complex
  • termination of RNA polymerase II transcription
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • CFT2
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • FIP1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • protein binding
  • GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
  • PAP1
  • mRNA cleavage and polyadenylation specificity factor complex
  • nucleoplasm
  • mRNA export from nucleus
  • mRNA polyadenylation
  • polynucleotide adenylyltransferase activity
  • PFS2
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • PTA1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • tRNA processing
  • termination of RNA polymerase II transcription, poly(A)-independent
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • PTI1
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • mRNA polyadenylation
  • mRNA cleavage
  • snoRNA 3'-end processing
  • RNA binding
  • RNA14
  • nucleus
  • mitochondrion
  • mRNA cleavage factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • protein heterodimerization activity
  • YSH1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • endoribonuclease activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA cleavage factor complex 6.9436E-27 10 20 10 6292
    mRNA cleavage and polyadenylation specificity factor complex 1.1808E-24 10 15 9 6292
    nucleoplasm part 6.6998E-15 10 245 10 6292
    nucleoplasm 1.4333E-14 10 264 10 6292
    nuclear lumen 3.41E-12 10 453 10 6292
    organelle lumen 1.5167E-10 10 660 10 6292
    intracellular organelle lumen 1.5167E-10 10 660 10 6292
    membrane-enclosed lumen 2.7426E-10 10 700 10 6292
    nuclear part 2.6498E-8 10 1103 10 6292
    protein complex 3.5941E-8 10 1137 10 6292
    macromolecular complex 1.3754E-6 10 1635 10 6292
    nucleus 1.2708E-5 10 2041 10 6292
    intracellular organelle part 3.8887E-5 10 2282 10 6292
    organelle part 3.8887E-5 10 2282 10 6292
    membrane-bounded organelle 5.9511E-3 10 3771 10 6292
    intracellular membrane-bounded organelle 5.9511E-3 10 3771 10 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA polyadenylation 2.1782E-23 10 19 9 6292
    RNA polyadenylation 7.36E-22 10 26 9 6292
    mRNA 3'-end processing 4.7454E-21 10 31 9 6292
    RNA 3'-end processing 1.0479E-19 10 42 9 6292
    mRNA cleavage 7.9859E-19 10 25 8 6292
    nucleic acid phosphodiester bond hydrolysis 1.9152E-16 10 46 8 6292
    mRNA processing 2.7553E-14 10 156 9 6292
    mRNA metabolic process 4.8031E-13 10 213 9 6292
    RNA processing 9.2527E-11 10 380 9 6292
    RNA metabolic process 6.1681E-9 10 954 10 6292
    termination of RNA polymerase II transcription 1.2334E-8 10 19 4 6292
    transcription termination 1.9016E-8 10 21 4 6292
    gene expression 1.2084E-7 10 1283 10 6292
    termination of RNA polymerase II transcription, poly(A)-independent 2.417E-7 10 9 3 6292
    cellular protein complex disassembly 2.5775E-7 10 39 4 6292
    protein complex disassembly 2.5775E-7 10 39 4 6292
    cellular macromolecular complex disassembly 2.8617E-7 10 40 4 6292
    macromolecular complex disassembly 2.8617E-7 10 40 4 6292
    nucleic acid metabolic process 3.2281E-7 10 1415 10 6292
    termination of RNA polymerase II transcription, poly(A)-coupled 3.45E-7 10 10 3 6292
    cellular component disassembly 4.2378E-7 10 44 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.9255E-7 10 1566 10 6292
    cellular nitrogen compound metabolic process 3.0471E-6 10 1770 10 6292
    nitrogen compound metabolic process 3.4296E-6 10 1791 10 6292
    cellular macromolecule metabolic process 3.9402E-5 10 2285 10 6292
    macromolecule metabolic process 5.1966E-5 10 2349 10 6292
    primary metabolic process 4.2311E-4 10 2896 10 6292
    cellular macromolecular complex subunit organization 4.8407E-4 10 259 4 6292
    cellular metabolic process 6.7219E-4 10 3033 10 6292
    metabolic process 1.0041E-3 10 3157 10 6292
    transcription from RNA polymerase II promoter 1.283E-3 10 335 4 6292
    macromolecular complex subunit organization 1.628E-3 10 357 4 6292
    histone dephosphorylation 3.1764E-3 10 2 1 6292
    transcription, DNA-dependent 5.7393E-3 10 503 4 6292
    RNA biosynthetic process 5.9477E-3 10 508 4 6292
    snoRNA 3'-end processing 7.9239E-3 10 5 1 6292
    transcription 8.0109E-3 10 552 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA binding 6.7544E-11 10 367 9 6292
    nucleic acid binding 1.4393E-8 10 666 9 6292
    binding 5.2522E-6 10 1294 9 6292
    protein heterodimerization activity 6.3436E-3 10 4 1 6292
    protein dimerization activity 9.5019E-3 10 6 1 6292
    polynucleotide adenylyltransferase activity 9.5019E-3 10 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle