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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CIC1
  • proteasome complex
  • nucleolus
  • protein catabolic process
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • protein binding, bridging
  • DBP9
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • DRS1
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • ERB1
  • nucleus
  • nucleolus
  • rRNA processing
  • molecular_function
  • HAS1
  • nuclear envelope
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • RNA-dependent ATPase activity
  • ATP-dependent RNA helicase activity
  • MAK21
  • Noc1p-Noc2p complex
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • MAK5
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • NIP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • molecular_function
  • NOC2
  • nucleus
  • Noc2p-Noc3p complex
  • mitochondrion
  • Noc1p-Noc2p complex
  • ribosomal subunit export from nucleus
  • ribosome biogenesis
  • ribosome assembly
  • molecular_function
  • NOP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA methyltransferase activity
  • S-adenosylmethionine-dependent methyltransferase activity
  • NOP4
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • PUF6
  • nucleus
  • nucleolus
  • regulation of transcription, mating-type specific
  • ribosome biogenesis
  • mRNA binding
  • specific transcriptional repressor activity
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • URB1
  • nucleolus
  • rRNA processing
  • processing of 27S pre-rRNA
  • molecular_function
  • YTM1
  • nucleus
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleolus 4.6603E-23 15 211 15 6292
    nuclear lumen 5.8229E-18 15 453 15 6292
    organelle lumen 1.7741E-15 15 660 15 6292
    intracellular organelle lumen 1.7741E-15 15 660 15 6292
    membrane-enclosed lumen 4.3281E-15 15 700 15 6292
    non-membrane-bounded organelle 5.0689E-13 15 959 15 6292
    intracellular non-membrane-bounded organelle 5.0689E-13 15 959 15 6292
    nuclear part 4.193E-12 15 1103 15 6292
    nucleus 4.4738E-8 15 2041 15 6292
    intracellular organelle part 2.3996E-7 15 2282 15 6292
    organelle part 2.3996E-7 15 2282 15 6292
    Noc1p-Noc2p complex 5.3053E-6 15 2 2 6292
    Noc complex 5.2834E-5 15 5 2 6292
    preribosome, large subunit precursor 1.8916E-4 15 9 2 6292
    membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    90S preribosome 7.0676E-4 15 17 2 6292
    intracellular organelle 1.4392E-3 15 4070 15 6292
    organelle 1.4445E-3 15 4071 15 6292
    preribosome 2.8479E-3 15 34 2 6292
    Noc2p-Noc3p complex 4.7627E-3 15 2 1 6292
    nucleolar part 4.9503E-3 15 45 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 9.5036E-20 15 346 15 6292
    ribonucleoprotein complex biogenesis 3.1258E-19 15 374 15 6292
    cellular component biogenesis 3.7988E-15 15 694 15 6292
    ribosomal large subunit biogenesis 5.0599E-13 15 65 8 6292
    ribosome assembly 4.0637E-9 15 64 6 6292
    organelle assembly 6.4574E-9 15 69 6 6292
    rRNA processing 6.878E-9 15 128 7 6292
    rRNA metabolic process 1.1078E-8 15 137 7 6292
    ribosomal large subunit assembly 2.6147E-8 15 41 5 6292
    ribonucleoprotein complex assembly 3.7332E-8 15 92 6 6292
    ribosomal subunit assembly 1.1913E-7 15 55 5 6292
    ncRNA processing 2.5161E-7 15 215 7 6292
    ncRNA metabolic process 8.4983E-7 15 257 7 6292
    cellular macromolecular complex assembly 2.1736E-6 15 182 6 6292
    RNA processing 1.1696E-5 15 380 7 6292
    cellular macromolecular complex subunit organization 1.68E-5 15 259 6 6292
    macromolecular complex assembly 2.677E-5 15 281 6 6292
    macromolecular complex subunit organization 1.0337E-4 15 357 6 6292
    cellular component assembly 1.5738E-4 15 385 6 6292
    processing of 27S pre-rRNA 6.2447E-4 15 16 2 6292
    RNA metabolic process 6.452E-4 15 954 8 6292
    gene expression 4.7582E-3 15 1283 8 6292
    cellular process 5.0732E-3 15 4426 15 6292
    obsolete_biological_process 8.6698E-3 15 60 2 6292
    nucleic acid metabolic process 8.9153E-3 15 1415 8 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ATP-dependent RNA helicase activity 4.1421E-7 15 28 4 6292
    RNA-dependent ATPase activity 4.7981E-7 15 29 4 6292
    RNA helicase activity 2.2203E-6 15 42 4 6292
    ATP-dependent helicase activity 3.8273E-6 15 48 4 6292
    purine NTP-dependent helicase activity 3.8273E-6 15 48 4 6292
    helicase activity 3.4409E-5 15 83 4 6292
    ATPase activity, coupled 3.364E-4 15 149 4 6292
    ATPase activity 1.2539E-3 15 211 4 6292
    nucleoside-triphosphatase activity 6.328E-3 15 329 4 6292
    hydrolase activity, acting on acid anhydrides 8.113E-3 15 353 4 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 8.113E-3 15 353 4 6292
    pyrophosphatase activity 8.113E-3 15 353 4 6292
    RNA binding 9.2962E-3 15 367 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle