Protein Overview: YLL032C

General Information:
Name(s) found:	YLL032C [SGD]
Description(s) found: Found 25 descriptions. SHOW ALL	Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene [SGD]
Organism:	Saccharomyces cerevisiae
Length:	825 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] ribosome [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNFKIYSTV ITTAFLQVPH LYTTNRLWKP IEAPFLVEFL QKRISSKELK NTKAICHIDP  60
   61 SWVNLNASFI RDDMISIKAT TDDMDLDAIC RISLPLPMNT NDLTAELEKM KRILLDLSEK 120
  121 FNLELIITKE PAYFTPEQTG ESKELCIYVH ALGFRSNLME CEPQLLAFVD LIKKNGMTLP 180
  181 PQHYIIEPME LNSYSVLPLY MGVDMENFKH ISRAFKTSIY APSLITLSRD LKANPQIFFS 240
  241 GAVHSLSLLA RKTLRESISV NSKSFFYRRL TNITPGKLLF IRKYYQQKVN QLILKYQSLI 300
  301 RVTNEYIEFQ SISTNLLEMV IKNFTIQVLH EIVEVQISLN ENCAMSPELI IDSFFGHTGN 360
  361 QIVVITPKED SFNQLIVVGN QSSTDEASDT SILHYLSDFI MGSNQVINPN LRQIKAIFEI 420
  421 HPDFEDFISG KKNGKLTRIM ELSACLIQLE MEEEDDNLYL NLVSDSFPDF KESFKNVINE 480
  481 FPAEESFFIP EVCHRPIIGT GGSLIQATMR KHNVFIQFSN SFNLPQNKIS MIRYDNVIIR 540
  541 CPRKNKANIC LAKNDLKQIV QEYDSLQSKT LIRFSSGQYR HILHVNGQKN IIGQIEKNEN 600
  601 VYIMIPLKEP LDGTSQLSIQ GNDENASRAA NELVNSAFGY EYEFKIDQEI DPNKEYEFYN 660
  661 LIVVPFLQIM NIIVTFEKDL ITFTFEKDTN ENTLTKAIEL LSNYLETQKT KIIFKKIIKK 720
  721 FVLGSASSKS NTSNSNTNGN FRSMNNAKSR TTIDNTSQSG ASPQRHKMPV ITTVGGAQAI 780
  781 KGYIPNTYYN GYGYGYGYTY EYDYNYANSN KAQTNNRHKY QNGRK

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		IRC8 LSM12 RPL38 YLL032C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	MLP2	#25 Asynchronous Prep3-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YLL032C	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..141]	deduced	N/A	No confident structure predictions are available.
2	View Details	[142..358]	MSA	2.159989	View MSA. No confident structure predictions are available.
3	View Details	[359..554]	PSI-BLAST	14.69897	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; S1 RNA-binding domain of polyribonucleotide phosphorylase, PNPase; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
4	View Details	[555..647]	PSI-BLAST	19.69897	Far upstream binding element, FBP, KH3 and KH4 domains
5	View Details	[648..745]	MSA	2.065989	View MSA. No confident structure predictions are available.
6	View Details	[746..825]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
structural constituent of ribosome	6.720012207401	bayes_pls_golite062009
structural molecule activity	6.15496287636596	bayes_pls_golite062009
transcription regulator activity	3.20568770944756	bayes_pls_golite062009
RNA binding	1.82714562401326	bayes_pls_golite062009
binding	1.5466198129438	bayes_pls_golite062009
nucleic acid binding	1.48613196553259	bayes_pls_golite062009
translation initiation factor activity	1.27539679024898	bayes_pls_golite062009
DNA binding	0.99813295819535	bayes_pls_golite062009
mRNA binding	0.871057743692364	bayes_pls_golite062009
transcription termination factor activity	0.76362333646107	bayes_pls_golite062009
protein binding	0.523813050066193	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	0.474251377131502	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	0.47336621289748	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	0.47336621289748	bayes_pls_golite062009
transcription factor activity	0.184749183964367	bayes_pls_golite062009
catalytic activity	0.10089766806364	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	6.9430052008157E-5	bayes_pls_golite062009

3

Term	Confidence	Notes
RNA binding	4.53756130039297	bayes_pls_golite062009
mRNA binding	4.29703395482722	bayes_pls_golite062009
nucleic acid binding	3.71927111604413	bayes_pls_golite062009
binding	3.03029468866374	bayes_pls_golite062009
transcription regulator activity	1.39930706524977	bayes_pls_golite062009
DNA binding	1.19211612853211	bayes_pls_golite062009
protein binding	1.16541072642796	bayes_pls_golite062009
mRNA 3'-UTR binding	0.496865429134247	bayes_pls_golite062009
transcription factor activity	0.272268621092333	bayes_pls_golite062009
catalytic activity	0.113112541746059	bayes_pls_golite062009

4

Term	Confidence	Notes
RNA binding	4.53756130039297	bayes_pls_golite062009
mRNA binding	4.29703395482722	bayes_pls_golite062009
nucleic acid binding	3.71927111604413	bayes_pls_golite062009
binding	3.03029468866374	bayes_pls_golite062009
transcription regulator activity	1.39930706524977	bayes_pls_golite062009
DNA binding	1.19211612853211	bayes_pls_golite062009
protein binding	1.16541072642796	bayes_pls_golite062009
mRNA 3'-UTR binding	0.496865429134247	bayes_pls_golite062009
transcription factor activity	0.272268621092333	bayes_pls_golite062009
catalytic activity	0.113112541746059	bayes_pls_golite062009

5

No functions predicted.

6

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle