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Protein Overview: ERT1

General Information:
Name(s) found: ERT1 / YBR239C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 529 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCTPDENDYK TSTDPDTSAN TNHTLEKKKR KKRKNTNVAC VNCSRLHVSC EAKRPCLRCI  60
   61 SKGLTATCVD APRKKSKYLA GIPNRELPMN IQPDLPPRKI MIPIYNNSSN SSLNVNNMGE 120
  121 QQKFTSPQHI VHKAKFLSNA ADSEYSILSN IIYQDTLSNK IPIDILYSNT NSTSNSTIGN 180
  181 SSNNSPTGTN TSPEETEMEK IRQLYSEQRA NIPPHPYPSS NQNVYSILLG PNSAKIVASQ 240
  241 VNLFANHFPL VPVDSADNSL NFKRLLPRDP SEKSSQINWD SSINQYYLNS ETVTFPELAI 300
  301 PLKRRKNHLV SVSLESCSPD AANIKSNVEW EHSLRYSTPM EIYTSINAPF SHTPGFHHLL 360
  361 VYLKHRFNQQ DLVKMCRSIA EFRPIFIACS VTLTEEDMIF MEQCYQRTLL EYVKFIAQIG 420
  421 TPTCIWRRNG QISYVNEEFE ILCGWTREEL LNKMTFIVEI MDDESVRDYF KTLSKVAYRD 480
  481 FRGSEKMKVC RLLSPIKGKI IHCCCMWTLK RDVSGLPLMI LGNFMPILN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3912: TAP-tagged, strain background includes hpc2(delta) Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ERT1 PEX22 2 Unpublished Fields Lab Data
    View Screen ERT1 POP8 2 Unpublished Fields Lab Data
    View Screen ERT1 NEM1 2 Unpublished Fields Lab Data
    View Screen ERT1 RNP1 2 Unpublished Fields Lab Data
    View Screen ERT1 ISU2 2 Unpublished Fields Lab Data
    View Screen ERT1 RDS2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ERT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] PSI-BLAST 9.0 Hap1 (Cyp1); HAP1
    2 View Details [172..353] deduced N/A No confident structure predictions are available.
    3 View Details [354..529] Pfam 13.346787 PAS fold No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.46021754022299 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.26455198324141 bayes_pls_golite062009
  • DNA binding
    		•  3.25588366587125 bayes_pls_golite062009
  • binding
    		•  2.32645838605286 bayes_pls_golite062009
  • transcription factor activity
    		•  2.20574348407066 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.54700248976411 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.34348800608209 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.28573362149629 bayes_pls_golite062009
  • transcription activator activity
    		•  0.335097584119319 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle