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Protein Overview: POP8

General Information:
Name(s) found: POP8 / YBL018C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 133 amino acids

    Gene Ontology:
    Cellular Component: ribonuclease MRP complex [IDALink to PubMed article]
    nucleolar ribonuclease P complex [IDALink to PubMed article]
    Biological Process: tRNA processing [TASLink to PubMed article]
    rRNA processing [TASLink to PubMed article]
    mRNA cleavage [IPILink to PubMed article]
    Molecular Function: ribonuclease P activity [IMPLink to PubMed article]
    ribonuclease MRP activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKTFREWQ YFKLSITSFD QDVDDAHAID QMTWRQWLNN ALKRSYGIFG EGVEYSFLHV  60
   61 DDKLAYIRVN HADKDTFSSS ISTYISTDEL VGSPLTVSIL QESSSLRLLE VTDDDRLWLK 120
  121 KVMEEEEQDC KCI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) POP1 POP3 POP4 POP5 POP6 POP8 RPP1
    View Details Hazbun TR, et al. (2003) POP1 POP3 POP4 POP5 POP6 POP8 RMP1 RPP1 SNM1
    View Details (MIPS) Mewes HW, et al. (2004) POP1 POP3 POP4 POP5 POP6 POP7 POP8 RPP1 RPR2
    View Details Gavin AC, et al. (2006) POP1 POP3 POP4 POP5 POP8 RPP1
    View Details Gavin AC, et al. (2002) POP1 POP3 POP4 POP5 POP6 POP8 RPP1
    View Details Qiu et al. (2008) POP1 POP3 POP4 POP5 POP6 POP7 POP8 RPP1 RPR2 SNM1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RMP1 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ERT1 POP8 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data POP8 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle