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A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication. A macromolecular complex containing both protein and RNA molecules. A ribonucleoprotein complex that contains a small nucleolar RNA (snoRNA) and associated proteins, and is found in eukaryotic cells. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: ribonuclease MRP complex
Acc: GO:0000172
Aspect: Cellular Component
Desc: A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
Synonyms:
  • ribonuclease mitochondrial RNA processing complex
  • RNase MRP complex
Proteins in PDR annotated with:
   This term: 40 [Search]
   Term or descendants: 40 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000172 - ribonuclease MRP complex (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle