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Protein Overview: FBpp0300311

General Information:
Name(s) found: FBpp0300311 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • type=protein; loc=X:complement(10133477..10133578,10133712..10133930,10134714..10135051,10135147..10135274,10135451..10135769,10136870..10136913,10137414..10137907); ID=FBpp0300311; name=Hk-PE; parent=FBgn0263220,FBtr0307877; dbxref=REFSEQ:NP_511104,GB_protein:AAF46567,FlyBase:FBpp0300311,FlyBase_Annotation_IDs:CG43388-PE; MD5=7902659cc3ec3585b99db603910e099f; length=547; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 547 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    voltage-gated potassium channel complex [ISS]
    Biological Process: potassium ion transport [IEA][ISS]
    transmembrane transport [IEA]
    flight behavior [IMP]
    oxidation reduction [IEA]
    Molecular Function: voltage-gated potassium channel activity [ISS]
    oxidoreductase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMALCNLNG DGSAAQSTSQ SQSQSPAATA AAAPLLPHSH SHTLQPESTP LLLGHEQSGS  60
   61 AAPEGSGGGD VTDGAVTSIE MPTVVADDAG VPPLPLPLPQ STPQPLLMAL PANLNFITGP 120
  121 TTQQLMIGNG AMGVIPSTND SNNNNNNNNN VDNTSDESNP VTIYRCRAPI ASLDCMEEFS 180
  181 RSISLGSNPA LPLRHGSTPT PGLRYKNLGK SGLRISNVGL GTWPVFSPGV SDDQAEAILK 240
  241 LAIESGINLF DISEAHSETE IGKILQRAGW KRTAYVITTK VYWSTKSEER GLSRKHIIEC 300
  301 VRASLQRLQL QYIDIVIIHK ADPMCPMEVV RAMSYVIQQG WAMYWGTARW SQVEIMEAYT 360
  361 NCRQFNCITP IVEQSEYHMF CREKCELYLP EMYNKIGVGL MAWGPLSMAL SDTQNGDKLF 420
  421 LPKGSFKTKS FSWTEDEINR NAALSPQGSW GKDRIDEGRR HCDRLRDLAA LAEKLGCSPT 480
  481 QLSIAWSLKH EPVQCLLLGA TSAEQLHQSL QSLQLLPRLS SSVMLELERI LENKPVRPPM 540
  541 ISTLALR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] deduced N/A No confident structure predictions are available.
    2 View Details [203..547] PSI-BLAST 90.221849 Voltage-dependent K+ channel beta subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • potassium channel activity
    		•  7.51963276589303 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  7.40239094355354 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  6.67507110634301 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  6.588881463055 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  6.52286930358188 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  6.50716590143831 bayes_pls_golite062009
  • cation channel activity
    		•  5.72172645555113 bayes_pls_golite062009
  • ion channel activity
    		•  5.15119282480682 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  5.07214658557001 bayes_pls_golite062009
  • channel activity
    		•  5.07214658557001 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  5.02503292701043 bayes_pls_golite062009
  • gated channel activity
    		•  4.92848832197692 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.63772951680109 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.58068601897668 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.46488926936937 bayes_pls_golite062009
  • catalytic activity
    		•  1.68179794468736 bayes_pls_golite062009
  • transporter activity
    		•  1.24767072239634 bayes_pls_golite062009
  • binding
    		•  1.15657176144267 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.03420335553507 bayes_pls_golite062009
  • potassium channel regulator activity
    		•  1.03017249802223 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.783004917746429 bayes_pls_golite062009
  • aldo-keto reductase activity
    		•  0.756121063182699 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.409822872480823 bayes_pls_golite062009
  • protein binding
    		•  0.220529867719707 bayes_pls_golite062009
  • 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity
    		•  0.207008954325429 bayes_pls_golite062009
  • trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
    		•  0.207008954325429 bayes_pls_golite062009
    		• 0.139676323362391 bayes_pls_golite062009
  • channel regulator activity
    		•  0.12154513851913 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle