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View Structure Prediction Details

Protein: FBpp0300311
Organism: Drosophila melanogaster
Length: 547 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0300311.

Description E-value Query
Range
Subject
Range
gi|902000 - gi|902000|gb|AAC46631.1| Hk protein
527.0 [0..1] [547..1]

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Predicted Domain #1
Region A:
Residues: [1-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMALCNLNG DGSAAQSTSQ SQSQSPAATA AAAPLLPHSH SHTLQPESTP LLLGHEQSGS  60
   61 AAPEGSGGGD VTDGAVTSIE MPTVVADDAG VPPLPLPLPQ STPQPLLMAL PANLNFITGP 120
  121 TTQQLMIGNG AMGVIPSTND SNNNNNNNNN VDNTSDESNP VTIYRCRAPI ASLDCMEEFS 180
  181 RSISLGSNPA LPLRHGSTPT PG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [203-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRYKNLGKSG LRISNVGLGT WPVFSPGVSD DQAEAILKLA IESGINLFDI SEAHSETEIG  60
   61 KILQRAGWKR TAYVITTKVY WSTKSEERGL SRKHIIECVR ASLQRLQLQY IDIVIIHKAD 120
  121 PMCPMEVVRA MSYVIQQGWA MYWGTARWSQ VEIMEAYTNC RQFNCITPIV EQSEYHMFCR 180
  181 EKCELYLPEM YNKIGVGLMA WGPLSMALSD TQNGDKLFLP KGSFKTKSFS WTEDEINRNA 240
  241 ALSPQGSWGK DRIDEGRRHC DRLRDLAALA EKLGCSPTQL SIAWSLKHEP VQCLLLGATS 300
  301 AEQLHQSLQS LQLLPRLSSS VMLELERILE NKPVRPPMIS TLALR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.221849
Match: 1exbA
Description: Voltage-dependent K+ channel beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
potassium channel activity 7.51963276589303 bayes_pls_golite062009
voltage-gated potassium channel activity 7.40239094355354 bayes_pls_golite062009
voltage-gated cation channel activity 6.67507110634301 bayes_pls_golite062009
metal ion transmembrane transporter activity 6.588881463055 bayes_pls_golite062009
voltage-gated ion channel activity 6.52286930358188 bayes_pls_golite062009
voltage-gated channel activity 6.50716590143831 bayes_pls_golite062009
cation channel activity 5.72172645555113 bayes_pls_golite062009
ion channel activity 5.15119282480682 bayes_pls_golite062009
passive transmembrane transporter activity 5.07214658557001 bayes_pls_golite062009
channel activity 5.07214658557001 bayes_pls_golite062009
substrate-specific channel activity 5.02503292701043 bayes_pls_golite062009
gated channel activity 4.92848832197692 bayes_pls_golite062009
ion transmembrane transporter activity 2.63772951680109 bayes_pls_golite062009
cation transmembrane transporter activity 2.58068601897668 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.46488926936937 bayes_pls_golite062009
catalytic activity 1.68179794468736 bayes_pls_golite062009
transporter activity 1.24767072239634 bayes_pls_golite062009
binding 1.15657176144267 bayes_pls_golite062009
transmembrane transporter activity 1.03420335553507 bayes_pls_golite062009
potassium channel regulator activity 1.03017249802223 bayes_pls_golite062009
substrate-specific transporter activity 0.783004917746429 bayes_pls_golite062009
aldo-keto reductase activity 0.756121063182699 bayes_pls_golite062009
oxidoreductase activity 0.409822872480823 bayes_pls_golite062009
protein binding 0.220529867719707 bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity 0.207008954325429 bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 0.207008954325429 bayes_pls_golite062009
0.139676323362391 bayes_pls_golite062009
channel regulator activity 0.12154513851913 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle