Protein Overview: HNF4A_RAT

General Information:
Name(s) found:	HNF4A_RAT [Swiss-Prot]
Description(s) found: Found 5 descriptions. SHOW ALL	Hepatocyte nuclear factor 4-alpha OS=Rattus norvegicus GN=Hnf4a PE=1 SV=3 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	474 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] transcription factor complex [IDA] cytoplasm [UNKNOWN][IDA]
Biological Process:	negative regulation of cell proliferation [UNKNOWN][IDA] positive regulation of transcription [IDA] response to cAMP [IEP] blood coagulation [UNKNOWN] regulation of transcription [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] positive regulation of gluconeogenesis [IMP] positive regulation of fatty acid biosynthetic process [IMP] acyl-CoA metabolic process [IDA] regulation of insulin secretion [IEA] sex differentiation [UNKNOWN][IEA] response to glucose stimulus [IDA] positive regulation of gene-specific transcription [UNKNOWN] negative regulation of cell growth [UNKNOWN] negative regulation of protein import into nucleus, translocation [IDA] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] negative regulation of peptidyl-tyrosine phosphorylation [IDA] regulation of gastrulation [UNKNOWN][IEA] establishment of tissue polarity [IDA] lipid homeostasis [UNKNOWN] ornithine metabolic process [UNKNOWN] SMAD protein signal transduction [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IDA] negative regulation of mitotic cell cycle [IDA] negative regulation of transcription factor activity [IDA] cell-cell junction organization [IDA] negative regulation of tyrosine phosphorylation of Stat5 protein [IDA] response to drug [IEP] lipid metabolic process [UNKNOWN][IEA] xenobiotic metabolic process [UNKNOWN] glucose homeostasis [IEA] cell differentiation [IMP] regulation of lipid metabolic process [UNKNOWN] regulation of microvillus assembly [IMP]
Molecular Function:	zinc ion binding [IEA] protein homodimerization activity [UNKNOWN][IMP] sequence-specific DNA binding [UNKNOWN][IMP] transcription factor binding [IPI] receptor binding [UNKNOWN] DNA binding [UNKNOWN][IDA] transcription factor activity [UNKNOWN][IMP][TAS] palmitoyl-CoA hydrolase activity [IDA] fatty acid binding [UNKNOWN][IPI] protein binding [UNKNOWN] transcription repressor binding [IPI] acyl-CoA binding [IPI] metal ion binding [IEA] RNA polymerase II transcription factor activity, enhancer binding [UNKNOWN][IEA] steroid hormone receptor activity [TAS] promoter binding [UNKNOWN][IEA] transcription activator activity [UNKNOWN][IEA] transcription activator binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLSKTLADM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGANLNS SNSLGVSALC  60
   61 AICGDRATGK HYGASSCDGC KGFFRRSVRK NHMYSCRFSR QCVVDKDKRN QCRYCRLKKC 120
  121 FRAGMKKEAV QNERDRISTR RSSYEDSSLP SINALLQAEV LSQQITSPIS GINGDIRAKK 180
  181 IANITDVCES MKEQLLVLVE WAKYIPAFCE LLLDDQVALL RAHAGEHLLL GATKRSMVFK 240
  241 DVLLLGNDYI VPRHCPELAE MSRVSIRILD ELVLPFQELQ IDDNEYACLK AIIFFDPDAK 300
  301 GLSDPGKIKR LRSQVQVSLE DYINDRQYDS RGRFGELLLL LPTLQSITWQ MIEQIQFIKL 360
  361 FGMAKIDNLL QEMLLGGSAS DAPHAHHPLH PHLMQEHMGT NVIVANTMPS HLSNGQMCEW 420
  421 PRPRGQAATP ETPQPSPPSG SGSESYKLLP GAITTIVKPP SAIPQPTITK QEAI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: HNF4A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: