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Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. The directed movement of substances within a cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of a protein from the cytoplasm to the nucleus. Any process that decreases the rate, frequency or extent of the vectorial transfer of a catenin protein from the cytoplasm into the nucleus, through the nuclear pore. The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. Any process that decreases the rate, frequency or extent of SMAD protein nuclear translocation. SMAD protein nuclear translocation is the vectorial transfer of a SMAD proteins from the cytoplasm into the nucleus, through the nuclear pore. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore. The vectorial transfer of a protein from the cytoplasm into the nucleus, through the nuclear pore and across the nuclear envelope.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of protein import into nucleus, translocation
Acc: GO:0033159
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
Synonyms:
  • negative regulation of protein import into cell nucleus, translocation
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033159 - negative regulation of protein import into nucleus, translocation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle