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Protein Overview: XPO1A_ARATH

General Information:
Name(s) found: XPO1A_ARATH [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Protein EXPORTIN 1A OS=Arabidopsis thaliana GN=XPO1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1075 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][TAS]
    cytoplasm [ISS]
    nuclear pore [ISS]
    Biological Process: pollen tube growth [IGI]
    pollen development [IGI]
    embryo sac development [IGI]
    protein export from nucleus [ISS]
    pollen germination [IGI]
    protein import into nucleus, docking [ISS]
    Molecular Function: protein binding [IPI]
    protein transporter activity [ISS]
    receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAEKLRDLS QPIDVGVLDA TVAAFFVTGS KEERAAADQI LRDLQANPDM WLQVVHILQN  60
   61 TNSLDTKFFA LQVLEGVIKY RWNALPVEQR DGMKNYISEV IVQLSSNEAS FRSERLYVNK 120
  121 LNVILVQIVK HDWPAKWTSF IPDLVAAAKT SETICENCMA ILKLLSEEVF DFSRGEMTQQ 180
  181 KIKELKQSLN SEFKLIHELC LYVLSASQRQ DLIRATLSAL HAYLSWIPLG YIFESTLLET 240
  241 LLKFFPVPAY RNLTIQCLTE VAALNFGDFY NVQYVKMYTI FIGQLRIILP PSTKIPEAYS 300
  301 SGSGEEQAFI QNLALFFTSF FKFHIRVLES TPEVVSLLLA GLEYLINISY VDDTEVFKVC 360
  361 LDYWNSLVLE LFDAHHNSDN PAVSASLMGL QPFLPGMVDG LGSQVMQRRQ LYSHPMSKLR 420
  421 GLMINRMAKP EEVLIVEDEN GNIVRETMKD NDVLVQYKIM RETLIYLSHL DHDDTEKQML 480
  481 RKLNKQLSGE EWAWNNLNTL CWAIGSISGS MAEDQENRFL VMVIRDLLNL CEITKGKDNK 540
  541 AVIASNIMYV VGQYPRFLRA HWKFLKTVVN KLFEFMHETH PGVQDMACDT FLKIVQKCKR 600
  601 KFVIVQVGEN EPFVSELLTG LATTVQDLEP HQIHSFYESV GNMIQAESDP QKRDEYLQRL 660
  661 MALPNQKWAE IIGQARHSVE FLKDQVVIRT VLNILQTNTS AATSLGTYFL SQISLIFLDM 720
  721 LNVYRMYSEL VSTNITEGGP YASKTSFVKL LRSVKRETLK LIETFLDKAE DQPHIGKQFV 780
  781 PPMMESVLGD YARNVPDARE SEVLSLFATI INKYKATMLD DVPHIFEAVF QCTLEMITKN 840
  841 FEDYPEHRLK FFSLLRAIAT FCFPALIKLS SPQLKLVMDS IIWAFRHTER NIAETGLNLL 900
  901 LEMLKNFQQS EFCNQFYRSY FMQIEQEIFA VLTDTFHKPG FKLHVLVLQQ LFCLPESGAL 960
  961 TEPLWDATTV PYPYPDNVAF VREYTIKLLS SSFPNMTAAE VTQFVNGLYE SRNDPSGFKN1020
 1021 NIRDFLVQSK EFSAQDNKDL YAEEAAAQRE RERQRMLSIP GLIAPNEIQD EMVDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..886] PSI-BLAST 91.09691 Karyopherin beta2
    2 View Details [887..1075] PSI-BLAST 106.0 Proteolytic fragment of CRM1 spanning six C-terminal HEAT repeats

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  3.48172991171337 bayes_pls_golite062009
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • structural molecule activity
    		•  2.87774614675757 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.61566088685247 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.34284977509828 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • signal sequence binding
    		•  2.11631489628537 bayes_pls_golite062009
  • RNA binding
    		•  1.98024495780436 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.91487015967262 bayes_pls_golite062009
  • actin binding
    		•  1.76244772281676 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.76231475025891 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • mRNA binding
    		•  1.71342954033223 bayes_pls_golite062009
  • DNA binding
    		•  1.62032607987786 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • transcription factor activity
    		•  0.923253759652909 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.83079633551839 bayes_pls_golite062009
  • translation regulator activity
    		•  0.82193201542158 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.803700928110921 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.662662274021266 bayes_pls_golite062009
  • signal transducer activity
    		•  0.662662274021266 bayes_pls_golite062009
  • hydrolase activity
    		•  0.42501390959416 bayes_pls_golite062009
  • importin-alpha export receptor activity
    		•  0.259676026705859 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • protein phosphatase binding
    		•  0.11022839198649 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0232727461674547 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle