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Protein Overview: dhs-29

General Information:
Name(s) found: dhs-29 / CE28011 [WormBase]
Description(s) found:
Found 18 descriptions.
SHOW ALL
  • WBGene00000992 locus:dhs-29 status:Confirmed UniProt:Q19843 protein_id:CCD67921.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 427 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: estrogen biosynthetic process [IEALink to PubMed article]
    poly-hydroxybutyrate biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    fatty acid biosynthetic process [IEALink to PubMed article]
    Molecular Function: estradiol 17-beta-dehydrogenase activity [IEALink to PubMed article]
    3-oxoacyl-[acyl-carrier-protein] reductase activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyrate dehydrogenase activity [IEALink to PubMed article]
    acetoacetyl-CoA reductase activity [IEALink to PubMed article]
    2-deoxy-D-gluconate 3-dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTSWAWKLW STLGVALRIL FIDIPMDIHR FLNLRQKSVQ GQTVIITGGG SGLGRAMALD  60
   61 FAKRKAKVAI IDVNKEGGLE TVKTIAAEGN MAKFWYCDIS DVDNMKKTAK EIEDTFGDVN 120
  121 IVICNAAILS FTSFMEISDE LLRKCLDVNI FGTINTIRAF LPKMETKNDG HIVCVCSIAG 180
  181 WSGETMGLSY CTSKFAVRGA MESLQMELRD RGLEGIKTTT LYPYFARTPM ILENNMRPTC 240
  241 TWFPFMSIRS CSKRMVDSIL KEKVHAFVPS YITLIPFVKN FCSLQVCRSL RNYLGVKYSA 300
  301 SDPSFCKLTL IEMSDYYKTP QLFWWLLIVP ALAINYISYA HPAAALNIPL IGSLVHKIGT 360
  361 EYPFVALLTN LFALVAHAGE ALYALYLCHK ANISFASTAK WVVQTFILGF PSLSILSRYE 420
  421 AKQRKNN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..292] PSI-BLAST 54.522879 Crystal structure of human 17-beta-hydroxysteroid dehydrogenase type XI
    2 View Details [293..427] PSI-BLAST 16.522879 No description for 2ju1A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  2.50453100919665 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • steroid dehydrogenase activity
    		•  1.75109362865449 bayes_pls_golite062009
  • retinoid binding
    		•  1.72614743805853 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  1.61759001796638 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.61095405873981 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.55012034958204 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  1.25489401408719 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  1.23679054027553 bayes_pls_golite062009
  • alcohol binding
    		•  1.07158175924364 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.867909552357575 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.665447800395781 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] reductase activity
    		•  0.604742541607263 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  0.439912268968251 bayes_pls_golite062009
  • binding
    		•  0.355184540089764 bayes_pls_golite062009
  • retinol binding
    		•  0.343379136183648 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.311551606659739 bayes_pls_golite062009
  • testosterone 17-beta-dehydrogenase activity
    		•  0.269929190680546 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  0.0822919343613215 bayes_pls_golite062009
  • ethanol binding
    		•  0.0448614072391299 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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