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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: acetoacetyl-CoA reductase activity
Acc: GO:0018454
Aspect: Molecular Function
Desc: Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
Synonyms:
  • D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity
  • NADPH:acetoacetyl-CoA reductase activity
  • D-3-hydroxyacyl-CoA reductase activity
  • NADP-linked acetoacetyl CoA reductase activity
  • (R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity
  • acetoacetyl coenzyme A reductase activity
  • (R)-3-hydroxyacyl-CoA dehydrogenase activity
  • hydroxyacyl coenzyme-A dehydrogenase activity
  • short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity
  • beta-ketoacyl-CoA reductase
Proteins in PDR annotated with:
   This term: 75 [Search]
   Term or descendants: 75 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0018454 - acetoacetyl-CoA reductase activity (interactive image map)

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