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View Structure Prediction Details

Protein: dhs-29
Organism: Caenorhabditis elegans
Length: 427 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dhs-29.

Description E-value Query
Range
Subject
Range
gi|187026172, gi... - gi|39594145|emb|CAE70255.1| Hypothetical protein CBG16756 [Caenorhabditis briggsae], gi|187026172|em...
gi|157770592 - gi|157770592|ref|XP_001677116.1| Hypothetical protein CBG16756 [Caenorhabditis briggsae AF16]
346.0 [0..1] [427..1]

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Predicted Domain #1
Region A:
Residues: [1-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTSWAWKLW STLGVALRIL FIDIPMDIHR FLNLRQKSVQ GQTVIITGGG SGLGRAMALD  60
   61 FAKRKAKVAI IDVNKEGGLE TVKTIAAEGN MAKFWYCDIS DVDNMKKTAK EIEDTFGDVN 120
  121 IVICNAAILS FTSFMEISDE LLRKCLDVNI FGTINTIRAF LPKMETKNDG HIVCVCSIAG 180
  181 WSGETMGLSY CTSKFAVRGA MESLQMELRD RGLEGIKTTT LYPYFARTPM ILENNMRPTC 240
  241 TWFPFMSIRS CSKRMVDSIL KEKVHAFVPS YITLIPFVKN FCSLQVCRSL RN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.522879
Match: 1yb1A
Description: Crystal structure of human 17-beta-hydroxysteroid dehydrogenase type XI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.09625241707629 bayes_pls_golite062009
retinol dehydrogenase activity 2.50453100919665 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
steroid dehydrogenase activity 1.75109362865449 bayes_pls_golite062009
retinoid binding 1.72614743805853 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.65338499044318 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 1.61759001796638 bayes_pls_golite062009
isoprenoid binding 1.61095405873981 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.55012034958204 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.47309297191111 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 1.25489401408719 bayes_pls_golite062009
fatty acid synthase activity 1.23679054027553 bayes_pls_golite062009
alcohol binding 1.07158175924364 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 0.867909552357575 bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 0.665447800395781 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.604742541607263 bayes_pls_golite062009
enoyl-CoA hydratase activity 0.439912268968251 bayes_pls_golite062009
binding 0.355184540089764 bayes_pls_golite062009
retinol binding 0.343379136183648 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 0.311551606659739 bayes_pls_golite062009
testosterone 17-beta-dehydrogenase activity 0.269929190680546 bayes_pls_golite062009
NADPH:quinone reductase activity 0.0822919343613215 bayes_pls_golite062009
ethanol binding 0.0448614072391299 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [293-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLGVKYSASD PSFCKLTLIE MSDYYKTPQL FWWLLIVPAL AINYISYAHP AAALNIPLIG  60
   61 SLVHKIGTEY PFVALLTNLF ALVAHAGEAL YALYLCHKAN ISFASTAKWV VQTFILGFPS 120
  121 LSILSRYEAK QRKNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 2ju1A
Description: No description for 2ju1A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle