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Protein Overview: elc-1

General Information:
Name(s) found: elc-1 / CE27039 [WormBase]
Description(s) found:
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  • WBGene00001236 locus:elc-1 status:Confirmed UniProt:Q9BKS1 protein_id:CCD73047.1 [WormBase]
  • gi|17556632|ref|NP_497405.1| ELongin C family member (elc-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|13435329|gb|AAK26155.1| Elongin c protein 1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE27039 WBGene00001236 locus:elc-1 status:Confirmed TR:Q9BKS1 protein_id:AAK26155.1 [wormpep150.fasta]
  • 27039 WBGene00001236 locus:elc-1 status:Confirmed TR:Q9BKS1 protein_id:AAK26155.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • predicted CDS, ELongin C (elc-1) [Caenorhabditis elegans]gi|13435329|gb|AAK26155.1| Elongin c protein 1 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:elc-1 status:Predicted TR:Q9BKS1 protein_id:AAK26155.1 [wormpep115.fasta.reversed]
  • CE27039 status:Predicted TR:Q9BKS1 protein_id:AAK26155.1 [wormpep80.hongbin]
  • CE27039 WBGene00001236 locus:elc-1 status:Confirmed UniProt:Q9BKS1_CAEEL protein_id:AAK26155.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE27039 WBGene00001236 locus:elc-1 status:Confirmed UniProt:Q9BKS1_CAEEL protein_id:AAK26155.1| [wormORF-contam.fasta]
  • Elongin c protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • ELongin C family member (elc-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE27039 WBGene00001236 locus:elc-1 status:Confirmed UniProt:Q9BKS1 protein_id:AAK26155.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE27039 WBGene00001236 locus:elc-1 status:Confirmed UniProt:Q9BKS1 protein_id:CCD73047.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • ELongin C OS=Caenorhabditis elegans GN=elc-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 124 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: anterior/posterior axis specification, embryo [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    meiotic anaphase II [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADQNNAIQC DQDAAQPKQY GGIEGPTSQY VKLVSSDDHE FIIKRELALT SGTIRAMLSG  60
   61 PGVYAENESN VVYFREIPSH VLQKVCQYFA YKVRYTHAAT EIPEFPIPPD VALELLMAAN 120
  121 FLDC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..124] PSI-BLAST 38.69897 Elongin C

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription elongation regulator activity
    		•  7.53002625989446 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  6.78934422958647 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  6.52079977531395 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.78412146341235 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.95822114853319 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.03732153795237 bayes_pls_golite062009
  • DNA binding
    		•  3.50992893425527 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.39650042677839 bayes_pls_golite062009
  • transcription factor activity
    		•  2.77967244868934 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  2.75167015020269 bayes_pls_golite062009
  • binding
    		•  2.73171412378045 bayes_pls_golite062009
  • cation channel activity
    		•  2.69496177380647 bayes_pls_golite062009
  • transporter activity
    		•  2.69283272202719 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  2.6326729238119 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  2.62698068681382 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  2.62598337348177 bayes_pls_golite062009
  • potassium channel activity
    		•  2.60418200634863 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.57638436739741 bayes_pls_golite062009
  • gated channel activity
    		•  2.55327516550249 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.55217077864016 bayes_pls_golite062009
  • ion channel activity
    		•  2.55187860471911 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.52366517282235 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.49612586394403 bayes_pls_golite062009
  • channel activity
    		•  2.47974023065334 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.47974023065334 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.47370185025265 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.46166567746833 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.36236066628439 bayes_pls_golite062009
  • ligase activity
    		•  1.75579073151181 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.71028791830657 bayes_pls_golite062009
  • protein binding
    		•  1.38558174459188 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.933012980583336 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.784594789263781 bayes_pls_golite062009
  • delayed rectifier potassium channel activity
    		•  0.72427436100801 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.278232864316812 bayes_pls_golite062009
  • catalytic activity
    		•  0.112500532859479 bayes_pls_golite062009
  • chromatin binding
    		•  0.0908724449159477 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.033499769837058 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle