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Protein Overview: cyn-13

General Information:
Name(s) found: cyn-13 / CE24152 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00000889 locus:cyn-13 Peptidyl-prolyl cis-trans isomerase E status:Confirmed UniProt:Q9U2S6 protein_id:CAB55151.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 331 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA fragmentation involved in apoptosis [IGILink to PubMed article][IMPLink to PubMed article]
    apoptosis [IGILink to PubMed article]
    protein folding [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    peptidyl-prolyl cis-trans isomerase activity [IEALink to PubMed article]
    nuclease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTNFPHNRK RTLYVGGFTE DVTEKVLMAA FIPFGDVVAI SIPMDYESGK HRGFGFVEFD  60
   61 MAEDAAMAID NMNESELFGK TIRVNFARPP KATERSQKPV WADDEWLKKY GRGGEAAAEE 120
  121 DGDAEKAATS SSSASTKLPR VYLGVKIGIR YIGRIVIELR TDVTPKTAEN FRCLCTGERG 180
  181 FGYEGSIFHR IIPKFMLQGG DFTKGDGTGG KSIYGTKFDD ENFTLRHTMP GTVSMANCGA 240
  241 NTNGSQFFIC TEKTDWLDGK HVVFGHVVEG MNIVRQVEQQ GTPSGKPQMV VKIVESGEIE 300
  301 PEKRIAAEKL AQKAVVPGAE IQEPLPQAME T

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..115] PSI-BLAST 18.0 Solution Structure of the RNA recognition motif in Peptidyl-prolyl cis-trans isomerase E
    2 View Details [116..179] FFAS03 1.44 Crystal Structure of cyclophilin from Plasmodium yoelii.
    3 View Details [180..331] PSI-BLAST 26.522879 No description for 2r99A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.61627913603672 bayes_pls_golite062009
  • snRNA binding
    		•  3.73900239153067 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • U1 snRNA binding
    		•  2.70790653818369 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • telomeric DNA binding
    		•  1.77419984594718 bayes_pls_golite062009
  • structural molecule activity
    		•  1.56454315220334 bayes_pls_golite062009
  • protein phosphatase 2B binding
    		•  1.48959622050982 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.14445638261529 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.970421843909091 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.87522799562879 bayes_pls_golite062009
  • transporter activity
    		•  0.628672636801176 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • hydrolase activity
    		•  0.520121701073354 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.505106991526286 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.220812525173636 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.182749906784328 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.096231856558874 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.059732432409948 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0510390778764699 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0484248928275733 bayes_pls_golite062009
  • receptor binding
    		•  0.0328291651348667 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  4.5592374722947E-4 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle