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View Structure Prediction Details

Protein: cyn-13
Organism: Caenorhabditis elegans
Length: 331 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cyn-13.

Description E-value Query
Range
Subject
Range
gi|91094253 - gi|91094253|ref|XP_969008.1| PREDICTED: similar to CG4554-PA [Tribolium castaneum]
207.0 [0..9] [302..5]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTNFPHNRK RTLYVGGFTE DVTEKVLMAA FIPFGDVVAI SIPMDYESGK HRGFGFVEFD  60
   61 MAEDAAMAID NMNESELFGK TIRVNFARPP KATERSQKPV WADDEWLKKY GRGGE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 2cqbA
Description: Solution Structure of the RNA recognition motif in Peptidyl-prolyl cis-trans isomerase E
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.61627913603672 bayes_pls_golite062009
snRNA binding 3.73900239153067 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.70790653818369 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
telomeric DNA binding 1.77419984594718 bayes_pls_golite062009
structural molecule activity 1.56454315220334 bayes_pls_golite062009
protein phosphatase 2B binding 1.48959622050982 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.14445638261529 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
structure-specific DNA binding 0.970421843909091 bayes_pls_golite062009
single-stranded DNA binding 0.87522799562879 bayes_pls_golite062009
transporter activity 0.628672636801176 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
hydrolase activity 0.520121701073354 bayes_pls_golite062009
transmembrane transporter activity 0.505106991526286 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
cytoskeletal protein binding 0.220812525173636 bayes_pls_golite062009
substrate-specific transporter activity 0.182749906784328 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.096231856558874 bayes_pls_golite062009
pyrophosphatase activity 0.059732432409948 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0510390778764699 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0484248928275733 bayes_pls_golite062009
receptor binding 0.0328291651348667 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4.5592374722947E-4 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [116-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAEEDGDAE KAATSSSSAS TKLPRVYLGV KIGIRYIGRI VIELRTDVTP KTAENFRCLC  60
   61 TGER

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.44
Match: 1z81A
Description: Crystal Structure of cyclophilin from Plasmodium yoelii.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [180-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFGYEGSIFH RIIPKFMLQG GDFTKGDGTG GKSIYGTKFD DENFTLRHTM PGTVSMANCG  60
   61 ANTNGSQFFI CTEKTDWLDG KHVVFGHVVE GMNIVRQVEQ QGTPSGKPQM VVKIVESGEI 120
  121 EPEKRIAAEK LAQKAVVPGA EIQEPLPQAM ET

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.522879
Match: 2r99A
Description: No description for 2r99A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle