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Protein Overview: CE23016

General Information:
Name(s) found: CE23016 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00013541 Lon protease homolog 2, peroxisomal status:Partially_confirmed UniProt:Q9XW87 protein_id:CAA22082.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 773 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein catabolic process [IEALink to PubMed article]
    proteolysis [IEALink to PubMed article]
    ATP-dependent proteolysis [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATPase activity [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    serine-type endopeptidase activity [IEALink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]
    ATP-dependent peptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIEENMELP VILVTSGVLL PGASLKIPIR SKLNIQTIEK YLTRSSNDNY VVIAYKVSTD  60
   61 KVYEVATIAY VEKLFGWTFN STVHYSLDVI GLHRANIDKL SLPTCIVSKV VDLNEAISNQ 120
  121 NAIEKLVTGA KIIASNSLTD KFSREIYSLI DEKEYGKLAD LCVSQMKFLG FMQLLEFLGA 180
  181 NGTDARVEMC IKWMNEKKDA NTLKLKVPNS LEASFPVDGK KRKIPNVKNQ VEQLEEKLNA 240
  241 IEFSDEVSDR VYSELHRLKS MNAQQSEYNI LMNWLELVSS LPWNTSTIDD IELHKARTIL 300
  301 TESHEAMDDV KERVLEHLAV CKMNNSVKGM ILCFTGPPGI GKTSIAKAIA ESMGRKFQRV 360
  361 SLGGIRDESD IRGHRRTYVA AMPGRIIEAL KTCKTNNPVF LLDEVDKLYS GNQGSPSAAL 420
  421 LELLDPEQNS TFHDHYLNIP FDVSKIMFIA TANDIDRLEP ALRDRLEIIE MSGYSLKEKV 480
  481 KICENHLLTR QLTKHCISHD YVKLERQAIV AMIEEYTMEA GVRQLERNVG AICRNVALRL 540
  541 AEALNSDPGA DVLPVMELPI QISASNIHKI LKNKHMKRVK IVEKMRPLPA GVCFGLSVTT 600
  601 IGGRVMPIEA SKSKGTGKIV TTGHLGKVLK ESILVAKGWL SANSERLGLG TLEDQDIHVH 660
  661 LPAGAVNKDG PSAGTGLACA LVSLATNIPL RSDAAVTGEI SLTGHVLPIG GVKEKVLAAQ 720
  721 REGLRRVVLP KSNEEEYLKM DEDIRLEMDV VLAETIEDVI GAMMDKSPVL AKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..584] PSI-BLAST 74.69897 Crystal Structure Analysis of ClpB
    2 View Details [585..773] PSI-BLAST 39.39794 Catalytic domain of E.coli Lon protease

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.62748401933955 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.55282098898104 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.5316131833172 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.53035702378505 bayes_pls_golite062009
  • binding
    		•  2.4974940028864 bayes_pls_golite062009
  • hydrolase activity
    		•  2.18454736627863 bayes_pls_golite062009
  • ATPase activity
    		•  2.04651885449197 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.87142752786895 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41477043612798 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • DNA binding
    		•  0.734219822349235 bayes_pls_golite062009
  • motor activity
    		•  0.70874549510465 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.640772201693186 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.63468044350616 bayes_pls_golite062009
  • GTP binding
    		•  0.621689261700018 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613020689836258 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.464456497491373 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • transporter activity
    		•  0.39890191703346 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • protein binding
    		•  0.378225828131122 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.22939561735194 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.0756212238097211 bayes_pls_golite062009
  • protein transporter activity
    		•  0.0071389922757723 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  1.35244774225337 bayes_pls_golite062009
  • hydrolase activity
    		•  1.18773479836745 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.18642233210148 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.05662964529454 bayes_pls_golite062009
  • structural molecule activity
    		•  0.95398657951177 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.927662190590087 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.831274075251956 bayes_pls_golite062009
  • peptidase activity
    		•  0.46678532223973 bayes_pls_golite062009
  • DNA binding
    		•  0.445830226393056 bayes_pls_golite062009
  • protein binding
    		•  0.398523921130957 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.345231097228971 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.343836551142441 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.321834241843501 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.277818626067707 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.258012116925759 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.257636057176676 bayes_pls_golite062009
  • ATPase activity
    		•  0.256995590197315 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.161393552073973 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.45

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle