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Protein Overview: myo1

General Information:
Name(s) found: myo1 / SPBC146.13c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • myosin type I [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1217 amino acids

    Gene Ontology:
    Cellular Component: myosin I complex [TASLink to PubMed article]
    site of polarized growth [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    actomyosin contractile ring [TASLink to PubMed article]
    prospore membrane [IDALink to PubMed article]
    medial cortex [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    membrane raft [IDALink to PubMed article]
    actin cortical patch [IDALink to PubMed article]
    Biological Process: barrier septum formation [IMPLink to PubMed article]
    actin nucleation [IDALink to PubMed article][IGILink to PubMed article]
    establishment or maintenance of cell polarity [IMPLink to PubMed article]
    membrane raft distribution [IMPLink to PubMed article]
    actin filament organization [IMPLink to PubMed article]
    regulation of endocytosis [IMPLink to PubMed article]
    endocytosis [ISSLink to PubMed article]
    actin cortical patch assembly [IGILink to PubMed article]
    actin cytoskeleton organization [IMPLink to PubMed article]
    ascospore wall assembly [IMPLink to PubMed article]
    actin cortical patch localization [IMPLink to PubMed article]
    positive regulation of actin nucleation [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    protein binding [IPILink to PubMed articleLink to PubMed article]
    actin binding [NAS]
    phospholipid binding [TASLink to PubMed article]
    microfilament motor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAILKRTNRA KAATAAAPNS TGKSNGIKKA VYTSTRKKTV GVDDLTLLSK ITDEEINKNL  60
   61 ELRFRNGEIY TYIGHVLISV NPFRDLGIYT MDILKSYQGK NRLETSPHVY AIAENAYYQM 120
  121 KSYHENQCII ISGESGAGKT EAAKRIMQYI THVSKSVGTE IERVSEIILA TNPLLESFGC 180
  181 AKTLRNNNSS RHGKYLEMIF NSGGVPVGAK ITNYLLEKNR IVNQVRNERN FHIFYQFTKS 240
  241 APQKYRDTYG IQGPENYVYT SACQCLSVDG ISDEKDFQGT MNAMKVIGIT EPEQDEIFRM 300
  301 LSIILWLGNI QFQEGQDGGS VISDKSITEF LGYLIGVPVA AIERALTIRI MQTQHGARRG 360
  361 SVYEVPLNPT QALAVRDALS MAIYNCLFDW IVERVNKALV TSDNSVSNSI GILDIYGFEI 420
  421 FENNSFEQLC INYVNEKLQQ IFIELTLKTE QEEYVREQIA WTPIKYFNNK VVCDLIESKR 480
  481 PPGLFAAMND AIATAHADSA AADSAFAQRL NFLSSNPHFE QRQNQFIVKH YAGDVTYSIT 540
  541 GMTDKNKDQL ATDILNLIHS SNNEFMKSIF PVAEESNSRR RPPTAGDRIK TSANDLVETL 600
  601 MKCQPSYIRT IKPNQTKSPN DYDQQMVLHQ IKYLGLQENI RIRRAGFAYR QAFDTFAQRF 660
  661 AVLSGKTSYA GEYTWQGDDK SACEQILKDT NIPSSEYQMG TSKVFIKNPE TLFALEDMRD 720
  721 KFWDTMATRI QRAWRSYVRR RSEAAACIQK LWNRNKVNME LERVRNEGTK LLQGKKQRRR 780
  781 YSILGSRKFY GDYLSASKPN GTLWNTCGLS QNDHVIFSMR CEVLVHKLGR TSKPSPRQLV 840
  841 LTKKNLYLVI TKIVDQKLTQ QVEKKFAVSS IDSVGLTNLQ DDWVAIRNKS SQNGDMFLRC 900
  901 FFKTEFITTL KRINRNIQVI VGPTIQYCRK PGKVQTVKTA KDETTKDYDY YKSGTIHVGT 960
  961 GLPPTSKSKP FPRLATGGST AAARGPRPVV QNKPAATKPV SMPAAKSKPA PMANPVSTAQ1020
 1021 QTQNRPPAPA MQARPNTTQA AAPVTSTTTT IKQATTVSAS KPAPSTVTSA ASSPSNISKP1080
 1081 SAPVANNVSK PSAVPPPPPP PPAEVEKKDL YLALYDFAGR SPNEMTIKKD EIIEIVQKEP1140
 1141 SGWWLALKNG AEGWVPATYV TEYKGSTPQT TASSTNVAAQ ANNNASPAEV NNLAGSLADA1200
 1201 LRMRASAVRG SDEEEDW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..707] PSI-BLAST 1000.0 Myosin S1, motor domain
    2 View Details [708..778] FFAS03 2.07 No description for 2ix7C was found.
    3 View Details [779..966] Pfam 69.69897 No description for PF06017.4 was found. No confident structure predictions are available.
    4 View Details [967..1217] PSI-BLAST 14.69897 No description for 2h8hA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin-dependent ATPase activity
    		•  5.83616693706338 bayes_pls_golite062009
  • microfilament motor activity
    		•  5.82833334737708 bayes_pls_golite062009
  • microtubule motor activity
    		•  4.51968578934603 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • actin binding
    		•  3.33639699088484 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • ADP binding
    		•  2.42564874799906 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • actin filament binding
    		•  2.24723363507804 bayes_pls_golite062009
  • myosin light chain binding
    		•  2.23966366728473 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • alpha-tubulin binding
    		•  1.792591628112 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • signal recognition particle binding
    		•  1.51332809264918 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  1.38366133153678 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.960508657568442 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.775560967092349 bayes_pls_golite062009
  • beta-tubulin binding
    		•  0.654735466720932 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.640772201693186 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.63468044350616 bayes_pls_golite062009
  • GTP binding
    		•  0.621689261700018 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • protein transporter activity
    		•  0.498432226280822 bayes_pls_golite062009
  • microtubule-severing ATPase activity
    		•  0.491769258942331 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • myosin I head/neck binding
    		•  0.370608920453309 bayes_pls_golite062009
  • myosin I heavy chain binding
    		•  0.370608920453309 bayes_pls_golite062009
  • plus-end directed microfilament motor activity
    		•  0.329356138573379 bayes_pls_golite062009
  • minus-end directed microfilament motor activity
    		•  0.329356138573379 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.286367085584159 bayes_pls_golite062009
  • signal transducer activity
    		•  0.286367085584159 bayes_pls_golite062009
  • myosin binding
    		•  0.274885859454447 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.213018989352421 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.169034229773346 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0775601177068852 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.0102645529518819 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • actin binding
    		•  4.94949685871786 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.41722924924158 bayes_pls_golite062009
  • actin filament binding
    		•  3.69427077755816 bayes_pls_golite062009
  • protein binding
    		•  3.13677730481089 bayes_pls_golite062009
  • binding
    		•  3.06905798270146 bayes_pls_golite062009
  • structural constituent of muscle
    		•  1.99054406740125 bayes_pls_golite062009
  • vinculin binding
    		•  1.63216315345235 bayes_pls_golite062009
  • transporter activity
    		•  1.30447542854757 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.08558010881058 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.951734365769481 bayes_pls_golite062009
  • signal transducer activity
    		•  0.951734365769481 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.820987609295422 bayes_pls_golite062009
  • structural molecule activity
    		•  0.794206109295456 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.570864043201529 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.371928447183203 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.277388904131159 bayes_pls_golite062009
  • receptor binding
    		•  0.0742205785215131 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle