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View Structure Prediction Details

Protein: myo1
Organism: Schizosaccharomyces pombe
Length: 1217 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for myo1.

Description E-value Query
Range		 Subject
Range
gi|74180466 - gi|74180466|dbj|BAE34176.1| unnamed protein product [Mus musculus]
 916.0 [0..2] [919..46]
gi|47940239 - gi|47940239|gb|AAH72094.1| LOC432141 protein [Xenopus laevis]
 914.0 [0..2] [979..46]
MYO1_NEUCR - Myosin-1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN...
MYO1_NEUCR - Myosin-1 OS=Neurospora crassa GN=myo-1 PE=3 SV=1
 906.0 [0..1] [1217..1]
gi|60654463 - gi|60654463|gb|AAX29922.1| myosin IF [synthetic construct]
 906.0 [0..26] [1163..3]
gi|157821107, gi... - gi|62651832|ref|XP_234942.3| PREDICTED: similar to myosin IF [Rattus norvegicus], gi|157821107|ref|N...
 906.0 [0..26] [1163..3]
MYO1F - myosin IF
gi|123980364, gi... - gi|157928118|gb|ABW03355.1| myosin IF [synthetic construct], gi|123980364|gb|ABM82011.1| myosin IF [...
 906.0 [0..26] [1163..3]

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Predicted Domain #1
Region A:
Residues: [1-707] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAILKRTNRA KAATAAAPNS TGKSNGIKKA VYTSTRKKTV GVDDLTLLSK ITDEEINKNL  60
   61 ELRFRNGEIY TYIGHVLISV NPFRDLGIYT MDILKSYQGK NRLETSPHVY AIAENAYYQM 120
  121 KSYHENQCII ISGESGAGKT EAAKRIMQYI THVSKSVGTE IERVSEIILA TNPLLESFGC 180
  181 AKTLRNNNSS RHGKYLEMIF NSGGVPVGAK ITNYLLEKNR IVNQVRNERN FHIFYQFTKS 240
  241 APQKYRDTYG IQGPENYVYT SACQCLSVDG ISDEKDFQGT MNAMKVIGIT EPEQDEIFRM 300
  301 LSIILWLGNI QFQEGQDGGS VISDKSITEF LGYLIGVPVA AIERALTIRI MQTQHGARRG 360
  361 SVYEVPLNPT QALAVRDALS MAIYNCLFDW IVERVNKALV TSDNSVSNSI GILDIYGFEI 420
  421 FENNSFEQLC INYVNEKLQQ IFIELTLKTE QEEYVREQIA WTPIKYFNNK VVCDLIESKR 480
  481 PPGLFAAMND AIATAHADSA AADSAFAQRL NFLSSNPHFE QRQNQFIVKH YAGDVTYSIT 540
  541 GMTDKNKDQL ATDILNLIHS SNNEFMKSIF PVAEESNSRR RPPTAGDRIK TSANDLVETL 600
  601 MKCQPSYIRT IKPNQTKSPN DYDQQMVLHQ IKYLGLQENI RIRRAGFAYR QAFDTFAQRF 660
  661 AVLSGKTSYA GEYTWQGDDK SACEQILKDT NIPSSEYQMG TSKVFIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1lkxA
Description: Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin-dependent ATPase activity 5.83616693706338 bayes_pls_golite062009
microfilament motor activity 5.82833334737708 bayes_pls_golite062009
microtubule motor activity 4.51968578934603 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
actin binding 3.33639699088484 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
hydrolase activity 2.55157966585974 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
ADP binding 2.42564874799906 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
actin filament binding 2.24723363507804 bayes_pls_golite062009
myosin light chain binding 2.23966366728473 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
alpha-tubulin binding 1.792591628112 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
signal recognition particle binding 1.51332809264918 bayes_pls_golite062009
plus-end-directed microtubule motor activity 1.38366133153678 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
structural constituent of muscle 0.960508657568442 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
GTPase activity 0.83849854735032 bayes_pls_golite062009
nucleic acid binding 0.775560967092349 bayes_pls_golite062009
beta-tubulin binding 0.654735466720932 bayes_pls_golite062009
guanyl nucleotide binding 0.640772201693186 bayes_pls_golite062009
guanyl ribonucleotide binding 0.63468044350616 bayes_pls_golite062009
GTP binding 0.621689261700018 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
protein transporter activity 0.498432226280822 bayes_pls_golite062009
microtubule-severing ATPase activity 0.491769258942331 bayes_pls_golite062009
DNA binding 0.479412476059825 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
myosin I head/neck binding 0.370608920453309 bayes_pls_golite062009
myosin I heavy chain binding 0.370608920453309 bayes_pls_golite062009
plus-end directed microfilament motor activity 0.329356138573379 bayes_pls_golite062009
minus-end directed microfilament motor activity 0.329356138573379 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
molecular transducer activity 0.286367085584159 bayes_pls_golite062009
signal transducer activity 0.286367085584159 bayes_pls_golite062009
myosin binding 0.274885859454447 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 0.213018989352421 bayes_pls_golite062009
G-protein coupled receptor activity 0.169034229773346 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009
structural constituent of ribosome 0.0102645529518819 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [708-778] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPETLFALED MRDKFWDTMA TRIQRAWRSY VRRRSEAAAC IQKLWNRNKV NMELERVRNE  60
   61 GTKLLQGKKQ R

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.07
Match: 2ix7C
Description: No description for 2ix7C was found.

Predicted Domain #3
Region A:
Residues: [779-966] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRYSILGSRK FYGDYLSASK PNGTLWNTCG LSQNDHVIFS MRCEVLVHKL GRTSKPSPRQ  60
   61 LVLTKKNLYL VITKIVDQKL TQQVEKKFAV SSIDSVGLTN LQDDWVAIRN KSSQNGDMFL 120
  121 RCFFKTEFIT TLKRINRNIQ VIVGPTIQYC RKPGKVQTVK TAKDETTKDY DYYKSGTIHV 180
  181 GTGLPPTS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 69.69897
Match: PF06017.4
Description: No description for PF06017.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [967-1217] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSKPFPRLAT GGSTAAARGP RPVVQNKPAA TKPVSMPAAK SKPAPMANPV STAQQTQNRP  60
   61 PAPAMQARPN TTQAAAPVTS TTTTIKQATT VSASKPAPST VTSAASSPSN ISKPSAPVAN 120
  121 NVSKPSAVPP PPPPPPAEVE KKDLYLALYD FAGRSPNEMT IKKDEIIEIV QKEPSGWWLA 180
  181 LKNGAEGWVP ATYVTEYKGS TPQTTASSTN VAAQANNNAS PAEVNNLAGS LADALRMRAS 240
  241 AVRGSDEEED W

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 2h8hA
Description: No description for 2h8hA was found.

Predicted functions:

Term Confidence Notes
actin binding 4.94949685871786 bayes_pls_golite062009
cytoskeletal protein binding 4.41722924924158 bayes_pls_golite062009
actin filament binding 3.69427077755816 bayes_pls_golite062009
protein binding 3.13677730481089 bayes_pls_golite062009
binding 3.06905798270146 bayes_pls_golite062009
structural constituent of muscle 1.99054406740125 bayes_pls_golite062009
vinculin binding 1.63216315345235 bayes_pls_golite062009
transporter activity 1.30447542854757 bayes_pls_golite062009
transmembrane transporter activity 1.08558010881058 bayes_pls_golite062009
molecular transducer activity 0.951734365769481 bayes_pls_golite062009
signal transducer activity 0.951734365769481 bayes_pls_golite062009
substrate-specific transporter activity 0.820987609295422 bayes_pls_golite062009
structural molecule activity 0.794206109295456 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.570864043201529 bayes_pls_golite062009
structural constituent of cytoskeleton 0.371928447183203 bayes_pls_golite062009
ion transmembrane transporter activity 0.277388904131159 bayes_pls_golite062009
receptor binding 0.0742205785215131 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle