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Protein Overview: gnr1

General Information:
Name(s) found: gnr1 / SPAC343.04c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • heterotrimeric G protein beta subunit Gnr1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 507 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    GID complex [ISS]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [ISS]
    negative regulation of gluconeogenesis [ISS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALDEKFQLE VIHLLLQFLN DYGYDESLKA LEKETGLVSE TEDVKRLKQA VLQGDWITAE  60
   61 AAFSIMQLRD ESKRKEAQFL LQKQRCLELA RSGAICEAIY VLQNFESTDF NKEKERLVSI 120
  121 ILESNNKSNN ELITKNGYGN TRLDLLNQLS EYISPEILLP KRRLEHLLQQ AKDYQVSSQV 180
  181 YHNVLKNFSF LSDYKADPSE LPTKEYHVFH DHSDEVWQIS YSHNGRYLAS ASKDKTAIIF 240
  241 DVVNLKRVFR LIGHIDTVAY IRWSPDDRYL LSCSCDKSVI LWDAFTGEKL RDYKHGFSVS 300
  301 CCCWLPDGLS FITGSPDCHI THWSLNGEIL YKWEDVNIYD MALTSDGTKL YIVGFEQLIN 360
  361 AEDKHIAIYS VETRECIKKI SLQSKVTSIC LSKDSKYALT NLEPHTTFLW DLEENRIVRQ 420
  421 YMGHKLGNFL IGSCFGGKDD TFVLSGSEDD KIRIWHRESG KLLATLSGHV KCVNYVAYNP 480
  481 VDPYQFASAG DDNTVRIWSN KDNPRRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..372] PSI-BLAST 13.221849 Crystal Structure analysis of the beta-propeller protein Ski8p
    2 View Details [373..412] PSI-BLAST 32.69897 Groucho/tle1, C-terminal domain
    3 View Details [413..507] PSI-BLAST 62.69897 No description for 2gnqA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
    		• 6.67009948605948 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • RNA binding
    		•  3.77273677738815 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.25521258308263 bayes_pls_golite062009
  • GTPase activity
    		•  3.20623818975951 bayes_pls_golite062009
  • structural molecule activity
    		•  2.6914565031145 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  2.48732877089832 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • translation initiation factor activity
    		•  2.29806492548141 bayes_pls_golite062009
  • snoRNA binding
    		•  2.27164613239345 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  2.10926890165617 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10348788067437 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.10036013463576 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.00420268007946 bayes_pls_golite062009
  • actin binding
    		•  1.95169936993576 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • myosin II binding
    		•  1.82354095216914 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.53722103498827 bayes_pls_golite062009
  • DNA binding
    		•  1.53482914288832 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • tubulin binding
    		•  1.07196649995443 bayes_pls_golite062009
  • mRNA binding
    		•  1.05053985350578 bayes_pls_golite062009
  • microtubule binding
    		•  1.04245147316521 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • transcription factor activity
    		•  0.897833210520351 bayes_pls_golite062009
  • kinase activity
    		•  0.807669232329985 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.805273887494167 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • transcription activator activity
    		•  0.724420384084538 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.634547834947756 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.624053529462119 bayes_pls_golite062009
  • protein kinase activity
    		•  0.544118712921054 bayes_pls_golite062009
  • transcription factor binding
    		•  0.469377587704245 bayes_pls_golite062009
  • actin filament binding
    		•  0.263920116138248 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.245000508226811 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.0803897416817422 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.0676565515282608 bayes_pls_golite062009
  • dynein binding
    		•  0.0650473020190896 bayes_pls_golite062009
  • receptor binding
    		•  0.0390635451962911 bayes_pls_golite062009
  • kinase binding
    		•  0.0366162235750993 bayes_pls_golite062009
  • protein kinase binding
    		•  0.00858004043229577 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle