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View Structure Prediction Details

Protein: gnr1
Organism: Schizosaccharomyces pombe
Length: 507 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gnr1.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
451.0 [0..19] [507..1187]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
436.0 [0..14] [507..1000]
gi|35214926, gi|... - gi|37523920|ref|NP_927297.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
434.0 [0..16] [507..619]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
427.0 [0..15] [507..1097]
gi|106891559, gi... - gi|148655047|ref|YP_001275252.1| WD-40 repeat-containing protein [Roseiflexus sp. RS-1], gi|14856715...
427.0 [0..15] [507..169]

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Predicted Domain #1
Region A:
Residues: [1-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALDEKFQLE VIHLLLQFLN DYGYDESLKA LEKETGLVSE TEDVKRLKQA VLQGDWITAE  60
   61 AAFSIMQLRD ESKRKEAQFL LQKQRCLELA RSGAICEAIY VLQNFESTDF NKEKERLVSI 120
  121 ILESNNKSNN ELITKNGYGN TRLDLLNQLS EYISPEILLP KRRLEHLLQQ AKDYQVSSQV 180
  181 YHNVLKNFSF LSDYKADPSE LPTKEYHVFH DHSDEVWQIS YSHNGRYLAS ASKDKTAIIF 240
  241 DVVNLKRVFR LIGHIDTVAY IRWSPDDRYL LSCSCDKSVI LWDAFTGEKL RDYKHGFSVS 300
  301 CCCWLPDGLS FITGSPDCHI THWSLNGEIL YKWEDVNIYD MALTSDGTKL YIVGFEQLIN 360
  361 AEDKHIAIYS VE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 1s4uX
Description: Crystal Structure analysis of the beta-propeller protein Ski8p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6.67009948605948 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.25521258308263 bayes_pls_golite062009
GTPase activity 3.20623818975951 bayes_pls_golite062009
structural molecule activity 2.6914565031145 bayes_pls_golite062009
myosin heavy chain kinase activity 2.48732877089832 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
translation initiation factor activity 2.29806492548141 bayes_pls_golite062009
snoRNA binding 2.27164613239345 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
G-protein-coupled receptor binding 2.10926890165617 bayes_pls_golite062009
transcription regulator activity 2.10348788067437 bayes_pls_golite062009
cytoskeletal protein binding 2.10036013463576 bayes_pls_golite062009
nucleic acid binding 2.00420268007946 bayes_pls_golite062009
actin binding 1.95169936993576 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
myosin II binding 1.82354095216914 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.53722103498827 bayes_pls_golite062009
DNA binding 1.53482914288832 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
tubulin binding 1.07196649995443 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
microtubule binding 1.04245147316521 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
transcription factor activity 0.897833210520351 bayes_pls_golite062009
kinase activity 0.807669232329985 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.805273887494167 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
transcription activator activity 0.724420384084538 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.634547834947756 bayes_pls_golite062009
transcription repressor activity 0.624053529462119 bayes_pls_golite062009
protein kinase activity 0.544118712921054 bayes_pls_golite062009
transcription factor binding 0.469377587704245 bayes_pls_golite062009
actin filament binding 0.263920116138248 bayes_pls_golite062009
transcription cofactor activity 0.245000508226811 bayes_pls_golite062009
protein serine/threonine kinase activity 0.0803897416817422 bayes_pls_golite062009
transcription corepressor activity 0.0676565515282608 bayes_pls_golite062009
dynein binding 0.0650473020190896 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
kinase binding 0.0366162235750993 bayes_pls_golite062009
protein kinase binding 0.00858004043229577 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [373-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRECIKKISL QSKVTSICLS KDSKYALTNL EPHTTFLWDL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.69897
Match: 1gxrA
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [413-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EENRIVRQYM GHKLGNFLIG SCFGGKDDTF VLSGSEDDKI RIWHRESGKL LATLSGHVKC  60
   61 VNYVAYNPVD PYQFASAGDD NTVRIWSNKD NPRRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 2gnqA
Description: No description for 2gnqA was found.

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