Protein Overview: nte1

General Information:
Name(s) found:	nte1 / SPCC4B3.04c [Sanger Pombe]
Description(s) found: Found 19 descriptions. SHOW ALL	lysophospholipase [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	1316 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [NAS] cytoplasm [IDA] integral to membrane [IEA] endoplasmic reticulum [ISS]
Biological Process:	phosphatidylcholine catabolic process [ISS] cellular lipid catabolic process [ISS]
Molecular Function:	lysophospholipase activity [ISS] carboxylesterase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDITDRILQN RIVSKVIFFV LRSVTLSLVS VTRFSLFLLS FATITVPKWA YKIVTYSLTI  60
   61 QFNFKSLLFL FFVSICVVIL VVRYRYLNKY ARLPHEAPIK EAKLGPDTNI RPSEPRIGFQ 120
  121 NYLDEFLSAI SIFGYLEKPV FVELARHIRT QRVAEGNTIY LGEQSSFILV VDGCFQVFTA 180
  181 PEKDSAEVVE EAGQPEYRLL TEVSNGAPLS SFFTVLELFT ELIPEATSKE NPFKSTTSSL 240
  241 RPGSSTTTEA GANNASKPHM PQPKKARIIA KAKIDTTIAV IPANAFHHLV HKFPNSSAQI 300
  301 VQVILTRFQR VTFSTGYEYL GLSDAIFSIE KNFNSLTAYE LPNYIRSDII DDFKKEAMSE 360
  361 HLSQASNESF IVLRSKGAQS RLSNQYFSKA FDKEHGNFVS DIDRSTANAG DLLSSTNPHS 420
  421 TLLSTSVGPL RKFPLNRSYS REVGDYDISA SFRDGLLQCI FKSLGVFNYE LKEDNDDLCT 480
  481 ENDSSEGDSD SLKKVDFLGQ IAMMSATDRE EVKSSIVVST KKSTILEFAK EIEIIFYKKG 540
  541 TTIVRQGDHA DGLYYIIDGF LDATCPSKLT FSTSYDTDLG MHSFMIKPGG IVNYQACVSN 600
  601 YRSFINVTAR SDVLVGFLPR SCLERIIDQE PLISLTIAKR LISLVPSLLL KLDFAVGWIH 660
  661 LNPDQVVYEK NDPSDCVYVV LNGRLRSIED ERGSARTQVD YFNEYGKGDS VGELEMLLNN 720
  721 RRSSTLFAIR DSELAKIPET LFNALSLSHP AVGLQLSKII ANRMNLLLNN KSMDGMQHQP 780
  781 HEKHSIRTLA IVPSSSTGLL ILFSQKLTSV LSVMGKSVKV LRQSSVLEHL GKHAFSRMGR 840
  841 FKLSSYLSDL EDKYDILIYV ADSGVGSAWL QTCIRQADCI YILAEADQNP NIGEYEQHLI 900
  901 AMKSTARKEL VLLHPERFCP SGLTRLWLKE RPWVYAHHHV QLRIGLDNEI SQNNEAKVFL 960
  961 NIIRAKVQNL HYGFRKYIDW KHLHPVYQAN RAQDSDFARL ARRICGKAIA LVLGGGGARG1020
 1021 ISQIGILYAL EEAGIPFDII GGTSIGAFNG GLYAWEADLV PMFGRAKKFC GRMANLWRFV1080
 1081 LDVTYPQAAY TTGHEFNRGI WKTFGEIHIE DFWLPFYANT TNITHSRMDI HSSGYAWRYI1140
 1141 RASMSLAGLV PPMLSDSGDM LLDGGYMDNL TVSHMQSLGA SSIFAIDVGS EDSREPMHYG1200
 1201 DTVSGVWALI SRWIPFIPKT SFPSLAEIQS RLTYVTSVAT GEKVKSMPGC FYMRPPVKDF1260
 1261 PTLEFGSFEK IYNVGYNYGK EYVEKLKTSH KLDDILSPRD TSKRHPKFLS SRRNSL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..92]	deduced	N/A	No confident structure predictions are available.
2	View Details	[93..338]	FFAS03	2.31	No description for 2pqqA was found.
3	View Details	[339..454]	deduced	N/A	No confident structure predictions are available.
4	View Details	[455..774]	PSI-BLAST	48.69897	Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase
5	View Details	[775..843]	PSI-BLAST	35.30103	Catabolite gene activator protein (CAP), C-terminal domain; Catabolite gene activator protein, N-terminal domain
6	View Details	[844..1005]	deduced	N/A	Confident ab initio structure predictions are available.
7	View Details	[1006..1316]	PSI-BLAST	37.522879	Patatin

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

No functions predicted.

3

No functions predicted.

4

Term	Confidence	Notes
ion channel activity	0.520384303065647	bayes_pls_golite062009
ligand-gated ion channel activity	0.497828140064889	bayes_pls_golite062009
ligand-gated channel activity	0.497828140064889	bayes_pls_golite062009
substrate-specific channel activity	0.48319462308643	bayes_pls_golite062009
channel activity	0.454459555295387	bayes_pls_golite062009
passive transmembrane transporter activity	0.454459555295387	bayes_pls_golite062009
gated channel activity	0.409785236987708	bayes_pls_golite062009
ion transmembrane transporter activity	0.341708851952942	bayes_pls_golite062009
cation channel activity	0.341210684071064	bayes_pls_golite062009
cation transmembrane transporter activity	0.105498264304027	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.0334592868738468	bayes_pls_golite062009

5

Term	Confidence	Notes
transcription regulator activity	2.19662303952524	bayes_pls_golite062009
nucleic acid binding	2.17489737456358	bayes_pls_golite062009
DNA binding	2.1344026805098	bayes_pls_golite062009
transcription factor activity	1.45035959828954	bayes_pls_golite062009
binding	0.554619018401844	bayes_pls_golite062009
sequence-specific DNA binding	0.279998232866747	bayes_pls_golite062009
transcription activator activity	0.078739212646842	bayes_pls_golite062009

6

No functions predicted.

7

Term	Confidence	Notes
phospholipase activity	3.87963112297417	bayes_pls_golite062009
phospholipase A2 activity	3.8689576466535	bayes_pls_golite062009
lipase activity	1.83391969295473	bayes_pls_golite062009
catalytic activity	1.681309422157	bayes_pls_golite062009
calcium-independent phospholipase A2 activity	1.65363998249183	bayes_pls_golite062009
fatty acid synthase activity	1.20394174397151	bayes_pls_golite062009
S-acyltransferase activity	1.07865077162953	bayes_pls_golite062009
hydrolase activity	0.949372513160363	bayes_pls_golite062009
[acyl-carrier-protein] S-malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
S-malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
carboxylesterase activity	0.431665185524913	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.39017969987234	bayes_pls_golite062009
acyltransferase activity	0.350701756346828	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	0.295883900540457	bayes_pls_golite062009
phospholipid binding	0.04135826589249	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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