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Protein Overview: dnm1

General Information:
Name(s) found: dnm1 / SPBC12C2.08 [Sanger Pombe]
Description(s) found:
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  • gi|984696|emb|CAA90821.1| dynamin Dnm1 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||T39373 dynamin-related protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19112806|ref|NP_596014.1| dynamin Dnm1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1175427|sp|Q09748.1|YB68_SCHPO RecName: Full=Dynamin-like protein C12C2.08 [NCBI NR]
  • dynamin Dnm1 [Sanger Pombe]
  • Dynamin-like protein C12C2.08 OS=Schizosaccharomyces pombe GN=SPBC12C2.08 PE=2 SV=1 [Swiss-Prot]
  • DYNAMIN FAMILY; CONTAINS DYNAMIN GTPASE EFFECTOR DOMAIN; MORPHOLOGY AND CORTICAL LOCALIZATION OF MITOCHONDRIA; SIMILAR TO S. CEREVISIAE DNM1: Q09748; [pompepVF.fasta]
  • DYNAMIN-RELATED PROTEIN; POSSIBLY CONTROLS MORPHOLOGY AND CORTICAL LOCALIZATION OF MITOCHONDRIA BY SIMILARITY TO YEAST DNM1: Q09748; [pompepV13]
  • Dynamin-like protein C12C2.08 [pompep4896]
  • |||dynamin family [pompepnew.fasta]
  • |||dynamin family|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • dynamin-related protein; possibly controls morphology and cortical localization of mitochondria by similarity to yeast dnm1 [Schizosaccharomyces pombe]gi|984696|emb|CAA90821.1| SPBC12C2.08 [Schizosaccharomyces pombe]gi|1175427|sp|Q09748|YB68_SCHPO Dynam [nrdb_11152004_Chlamydomonas]
  • |dnm1||dynamin family|Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q09748) Dynamin-like protein C12C2.08 [pompep4896_normal_reversed]
  • |dnm1||dynamin Dnm1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBC12C2.08 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC12C2.08 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 781 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrial outer membrane [ISSLink to PubMed article]
    Biological Process: mitochondrion inheritance [IMPLink to PubMed article]
    cellular membrane fusion [TASLink to PubMed article]
    peroxisome organization [IGILink to PubMed article]
    mitochondrion localization, microtubule-mediated [IGILink to PubMed article]
    mitochondrial DNA inheritance [IMPLink to PubMed article]
    mitochondrion organization [IMPLink to PubMed article]
    mitochondrial fission [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: GTP binding [ISSLink to PubMed article]
    GTPase activity [ISSLink to PubMed article]
    motor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQLIPLVNQ LQDLVYNTIG SDFLDLPSIV VVGSQSCGKS SVLENIVGKD FLPRGTGIVT  60
   61 RRPLILQLIN LKRKTKNNHD EESTSDNNSE ETSAAGETGS LEGIEEDSDE IEDYAEFLHI 120
  121 PDTKFTDMNK VRAEIENETL RVAGANKGIN KLPINLKIYS TRVLNLTLID LPGLTKIPVG 180
  181 DQPTDIEAQT RSLIMEYISR PNSIILAVSP ANFDIVNSEG LKLARSVDPK GKRTIGVLTK 240
  241 LDLMDQGTNA MDILSGRVYP LKLGFVATVN RSQSDIVSHK SMRDALQSER SFFEHHPAYR 300
  301 TIKDRCGTPY LAKTLSNLLV SHIRERLPDI KARLSTLISQ TQQQLNNYGD FKLSDQSQRG 360
  361 IILLQAMNRF ANTFIASIDG NSSNIPTKEL SGGARLYSIF NNVFTTALNS IDPLQNLSTV 420
  421 DIRTAILNST GSRATLFLSE MAFDILVKPQ LNLLAAPCHQ CVELVYEELM KICHYSGDSD 480
  481 ISHFPKLQTA LVETVSDLLR ENLTPTYSFV ESLIAIQSAY INTNHPDFLG VQGAMAVVLS 540
  541 RKEQNRLMLS QENDEPISSA LDTVKPDGIE LYSSDPDTSV KSITNKATNE ITTLKSDDSA 600
  601 KMQPLDVLAS KRYNNAFSTE TAERKTFLSY VFGANNATRK AMSIDKSSSY PLNDSLSGGD 660
  661 TNHKNNHPLK MTDLSNEVET MALEDMSERE EVEVDLIKEL ITSYFNLTRK IIIDQVPKVI 720
  721 MHLLVNASKD AIQNRLVSKL YREDFFDTLL IEDENVKSER EKCERLLSVY NQANKIISTV 780
  781 F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..352] PSI-BLAST 92.221849 Dynamin G domain
    2 View Details [353..584] Pfam 44.638272 No description for PF01031.11 was found. No confident structure predictions are available.
    3 View Details [585..685] deduced N/A No confident structure predictions are available.
    4 View Details [686..781] Pfam 41.744727 No description for PF02212.9 was found. Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  6.13591371239337 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  2.65631438185675 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • microfilament motor activity
    		•  2.51786963027655 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • actin binding
    		•  2.2973522188675 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • DNA binding
    		•  2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • actin filament binding
    		•  1.28204719195916 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  0.92105578610354 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887108427603557 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.683309012097319 bayes_pls_golite062009
  • signal transducer activity
    		•  0.683309012097319 bayes_pls_golite062009
  • glutamate receptor binding
    		•  0.67946233728984 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • protein transporter activity
    		•  0.498432226280822 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.46552249844591 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • signal recognition particle binding
    		•  0.29390189699022 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.213018989352421 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.089234257580272 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009
  • minus-end-directed microtubule motor activity
    		•  0.068779631341469 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle