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Protein Overview: slp1

General Information:
Name(s) found: slp1 / SPAC821.08c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • sleepy homolog Slp1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cell division site [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    spindle [IDALink to PubMed article]
    condensed nuclear chromosome kinetochore [IDALink to PubMed article]
    mitotic checkpoint complex [IDALink to PubMed article]
    Biological Process: mitotic cell cycle spindle assembly checkpoint [IGILink to PubMed article]
    DNA replication checkpoint [IGILink to PubMed article]
    activation of mitotic anaphase-promoting complex activity [TASLink to PubMed article]
    mitotic sister chromatid segregation [IGILink to PubMed article]
    positive regulation of mitotic metaphase/anaphase transition [IPILink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    spindle checkpoint [IPILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    anaphase-promoting complex binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIAGNSSTI SPTFSTPTKK RNLVFPNSPI TPLHQQALLG RNGRSSKRCS PKSSFIRNSP  60
   61 KIDVVNTDWS IPLCGSPRNK SRPASRSDRF IPSRPNTANA FVNSISSDVP FDYSESVAEA 120
  121 CGFDLNTRVL AFKLDAPEAK KPVDLRTQHN RPQRPVVTPA KRRFNTTPER VLDAPGIIDD 180
  181 YYLNLLDWSN LNVVAVALER NVYVWNADSG SVSALAETDE STYVASVKWS HDGSFLSVGL 240
  241 GNGLVDIYDV ESQTKLRTMA GHQARVGCLS WNRHVLSSGS RSGAIHHHDV RIANHQIGTL 300
  301 QGHSSEVCGL AWRSDGLQLA SGGNDNVVQI WDARSSIPKF TKTNHNAAVK AVAWCPWQSN 360
  361 LLATGGGTMD KQIHFWNAAT GARVNTVDAG SQVTSLIWSP HSKEIMSTHG FPDNNLSIWS 420
  421 YSSSGLTKQV DIPAHDTRVL YSALSPDGRI LSTAASDENL KFWRVYDGDH VKRPIPITKT 480
  481 PSSSITIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] PSI-BLAST 3.221849 Surface layer protein
    2 View Details [167..488] PSI-BLAST 57.221849 PAF-AH Holoenzyme: Lis1/Alfa2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
    		• 6.67009948605948 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • RNA binding
    		•  3.77273677738815 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.25521258308263 bayes_pls_golite062009
  • GTPase activity
    		•  3.23750443966606 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • actin binding
    		•  2.82238441497141 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • snoRNA binding
    		•  2.27164613239345 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.10542371217826 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10348788067437 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.00420268007946 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • tubulin binding
    		•  1.71990413056683 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.59258100795958 bayes_pls_golite062009
  • microtubule binding
    		•  1.58000769768764 bayes_pls_golite062009
  • DNA binding
    		•  1.53482914288832 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47097979074281 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.29070899918311 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • dynactin binding
    		•  1.11168036488973 bayes_pls_golite062009
  • actin filament binding
    		•  1.10832047454002 bayes_pls_golite062009
  • mRNA binding
    		•  1.05053985350578 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • dynein binding
    		•  0.94661325264568 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • transcription factor activity
    		•  0.897833210520351 bayes_pls_golite062009
  • transporter activity
    		•  0.807925044108643 bayes_pls_golite062009
  • transcription activator activity
    		•  0.724420384084538 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.625780732991652 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.535041400676017 bayes_pls_golite062009
  • transcription factor binding
    		•  0.469377587704245 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.428715007921149 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.414491774707324 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  0.251120087240234 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.245000508226811 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.220747580531792 bayes_pls_golite062009
  • hydrolase activity
    		•  0.181211933860468 bayes_pls_golite062009
  • myosin binding
    		•  0.16849147094895 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • kinase activity
    		•  0.08280915441667 bayes_pls_golite062009
  • receptor binding
    		•  0.0390635451962911 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle