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Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex that regulates the mitotic metaphase/anaphase transition. Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the mitotic cell cycle. Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. Any process that activates or increases the frequency, rate or extent of the mitotic metaphase to anaphase transition. Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. Any process that activates or increases the frequency, rate or extent of mitosis. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle. Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. Any process that activates, maintains or increases the rate of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. Any process that modulates the frequency, rate or extent of the onset of anaphase (chromosome movement) in the mitotic cell cycle. The cell cycle process whereby a cell progresses from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: activation of mitotic anaphase-promoting complex activity
Acc: GO:0007092
Aspect: Biological Process
Desc: Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex that regulates the mitotic metaphase/anaphase transition.
Synonyms:
  • mitotic anaphase-promoting complex activation
  • mitotic APC activator
  • activation of ubiquitin ligase activity of anaphase promoting complex during mitotic cell cycle
  • activation of ubiquitin ligase activity of anaphase-promoting complex during mitotic cell cycle
  • activation of ubiquitin ligase activity of APC during mitotic cell cycle
  • mitotic anaphase-promoting complex activator
  • mitotic anaphase promoting complex activation
  • anaphase promoting complex activation during mitotic cell cycle
  • mitotic APC activation
  • mitotic anaphase promoting complex activator
  • anaphase-promoting complex activation during mitotic cell cycle
  • APC activation during mitotic cell cycle
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007092 - activation of mitotic anaphase-promoting complex activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle