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Protein Overview: sck1

General Information:
Name(s) found: sck1 / SPAC1B9.02c [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • serine/threonine protein kinase Sck1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 696 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: protein amino acid phosphorylation [TASLink to PubMed article]
    regulation of trehalose metabolic process [IMPLink to PubMed article]
    cAMP-mediated signaling [IMPLink to PubMed article]
    regulation of conjugation with cellular fusion [IGILink to PubMed article]
    Molecular Function: ATP binding [ICLink to PubMed article]
    protein serine/threonine kinase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEIFGKLHR SSNSENTNQA SPSTIQSHST QPVLSNDHST KVNDYEGKEG ASSNGYDPVF  60
   61 MSDRMKMRYN EITAQLHKEQ SLKEDKESGS NSSESNGITP MGTYSEKPKL LQSRTPPSSC 120
  121 YIRHDTVVPK DKNGQHAFGR LYVRLHQGRD LNVKSVNAQP YAVITFEKTQ VMVPPPFKDI 180
  181 DGGIPISIPS KNRPLAGSAS GSSSGLHSEL MLADVRCPHW DFETVFDVTK MKSQMVVSVY 240
  241 DKYEDDKFLG SVKITPIFLH EYVQEAWYKL EPLDLTKSLE GEIKVETIYE HIEHVRYGPE 300
  301 DFTALRLIGK GTFGQVYLVR KNDTNRIYAM KKISKKLIVR KKEVTHTLGE RNILVRTSLD 360
  361 ESPFIVGLKF SFQTASDLYL ITDYMSGGEL FWHLQHEGRF PEQRAKFYIA ELVLALEHLH 420
  421 KHDIIYRDLK PENILLDADG HIALCDFGLS KANLSANATT NTFCGTTEYL APEVLLEDKG 480
  481 YTKQVDFWSL GVLVFEMCCG WSPFYAPDVQ QMYRNIAFGK VRFPKGVLSS EGRSFVRGLL 540
  541 NRNPNHRLGA VADTTELKEH PFFADINWDL LSKKKVQPPF KPNVQNDLDV SNFDKEFTNT 600
  601 NVKNINIVSN VDPANASTPL SNTIQDRFRG FTFVNKSIDE QFQNLGLQEN EETDNLHACR 660
  661 TTTHSSVNSI NSHGNPRTVD ANDPVADTVF GETFEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..125] deduced N/A No confident structure predictions are available.
    2 View Details [126..296] FFAS03 5.91 No description for 2ep6A was found.
    3 View Details [297..566] PSI-BLAST 70.045757 3-phosphoinositide dependent protein kinase-1 Pdk1
    4 View Details [567..696] PSI-BLAST 95.69897 Pkb kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • calmodulin-dependent protein kinase activity
    		•  4.31938467136214 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • protein binding
    		•  2.276111749106 bayes_pls_golite062009
  • tubulin binding
    		•  2.18641675163967 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.12615078788254 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • microtubule binding
    		•  1.88110801192607 bayes_pls_golite062009
  • actin binding
    		•  1.87817875565699 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.7769021678395 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.6878868450299 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  1.62657794525303 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.6084489855403 bayes_pls_golite062009
  • receptor activity
    		•  1.57112777506542 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.4571078357189 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  1.28511591054866 bayes_pls_golite062009
  • kinase binding
    		•  1.26086833316556 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  1.25285260301349 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • protein kinase binding
    		•  1.06030596516506 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.959360414036299 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • actin filament binding
    		•  0.794152600084 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.794058505655489 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.775404673285876 bayes_pls_golite062009
  • DNA binding
    		•  0.714163549867672 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.612883428421652 bayes_pls_golite062009
  • protein complex binding
    		•  0.599713385230491 bayes_pls_golite062009
  • transcription factor activity
    		•  0.563262875317016 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.450699332958421 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  0.26602283402868 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  0.26602283402868 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.237134032032089 bayes_pls_golite062009
  • SH2 domain binding
    		•  0.226760162354251 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.148194101970458 bayes_pls_golite062009
  • growth factor binding
    		•  0.0526340287295695 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.0506751594607393 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0040394359628233 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle