Protein Overview: nak1

General Information:
Name(s) found:	nak1 / SPBC17F3.02 [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T39722 serine/threonine protein kinase (EC 2.7.1.-) [similarity] - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|3719385\|gb\|AAC63343.1\| N-terminal serine/threonine protein kinase [Schizosaccharomyces pombe] [NCBI NR] gi\|3417438\|emb\|CAA20324.1\| PAK-related kinase Nak1 [Schizosaccharomyces pombe] [NCBI NR] gi\|26396999\|sp\|O75011.1\|NAK1_SCHPO RecName: Full=Serine/threonine-protein kinase nak1; AltName: Full=N-rich kinase 1 [NCBI NR] gi\|19112815\|ref\|NP_596023.1\| PAK-related kinase Nak1 [Schizosaccharomyces pombe] [NCBI NR] PAK-related kinase Nak1 [Sanger Pombe] Serine/threonine-protein kinase nak1 OS=Schizosaccharomyces pombe GN=nak1 PE=1 SV=1 [Swiss-Prot] N-TERMINAL SERINE/THREONINE PROTEIN KINASE: O75011; [pompepVF.fasta] Serine/threonine-protein kinase nak1 (EC 2.7.1.37) (N-rich kinase 1) [pompep4896] \|nak1\|\|N-terminal protein kinase [pompepnew.fasta] \|nak1\|\|N-terminal protein kinase\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] n-terminal serine/threonine protein kinase. [Schizosaccharomyces pombe]gi\|3719385\|gb\|AAC63343.1\| N-terminal serine/threonine protein kinase [Schizosaccharomyces pombe]gi\|3417438\|emb\|CAA20324.1\| SPBC17F3.02 [Schizosaccharomyces pombe]gi\|26396999\|sp\|O750 [nrdb_11152004_Chlamydomonas] \|nak1\|\|PAK-related kinase Nak1\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pompep2242005.fasta] (O75011) Serine/threonine-protein kinase nak1 (EC 2.7.1.37) (N-rich kinase 1) [pompep4896_normal_reversed] \|nak1\|orb3, mor4\|PAK-related kinase Nak1\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] hypothetical protein SPBC17F3.02 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] N-terminal serine/threonine protein kinase [Schizosaccharomyces pombe] [nr-271106-contam.fasta] SPBC17F3.02 [Schizosaccharomyces pombe] [nr-271106-contam.fasta] Serine/threonine-protein kinase nak1 (N-rich kinase 1) [nr-271106-contam.fasta] Serine/threonine-protein kinase nak1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nak1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	652 amino acids
Gene Ontology:
Cellular Component:	medial cortex [TAS] cytoplasm [IDA] cell cortex of cell tip [TAS] spindle pole body [IDA] cytosol [IDA] actin cortical patch [TAS]
Biological Process:	regulation of cell shape [IGI] regulation of cell separation during cytokinesis [IMP] establishment or maintenance of cell polarity [IMP] cytokinetic cell separation [IGI] protein amino acid phosphorylation [TAS] maintenance of cell polarity [TAS] cellular response to stress [IGI] regulation of bipolar cell growth [IGI] actin filament reorganization involved in cell cycle [IMP] establishment or maintenance of actin cytoskeleton polarity [IMP] actin cortical patch localization [IMP] cellular protein localization [IGI ] regulation of monopolar cell growth [IGI]
Molecular Function:	ATP binding [IC] protein binding [IPI ] protein serine/threonine kinase activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENNTASSPY TKLELVGRGS YGAVYRGICN LTKETVAIKI LNLDTDEDEV SDIQKEVAVL  60
   61 SELKQSDVEN IIKYHGSYLV GTNLWIIMDY CHGGSVRTLM EAGPISEPCI SLILRETLQA 120
  121 LKFIHHAGII HRDIKAANIL VSMSGNVKLC DFGVAAELNI NRRKRITFIG TPYWMAPEVI 180
  181 RDGQEYNVMA DIWSLGITAY EIATGSPPHA KEDPFRAVYL IAHTAPPRLN GNFSALLKEF 240
  241 IASCLQDVPQ RRLDSSELLK SKFIKQYSRM SISELTNVVK RYDTWQAAGG IPQTLLLGEE 300
  301 ADDGSDPDQE TSDTAASDDG WEFGTIKQGQ SNVSSITGTS TSTTTAATSS TTVTGTVIPK 360
  361 SSTVHEPPSS NDSHPLLQLF KDSKISDDDS PSNAEGASTE DSKGEVSYSQ IELPSLDSSN 420
  421 LSSKKSTIQS KHTKQAEDYD LFVGRTRSNS KTSSDQSIKR PLPRVVQRQK TSLGKRGISM 480
  481 SPMKPGLRMP SSFDLQSRSI SMGAFEQLST PLEAPAHKHS AVLQPLEVNR SISIPPPKSI 540
  541 SPSILHKPSL ESASSTPKIS SCSSTPKPFN SKLRAHLPPL SIGSPAVQPL ANDNYDSLGV 600
  601 RGLNMELFND YPGNMHNIKS VLSLEIDIVL GEMDACLKSL ECNLLNRKAY NE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
phosphotransferase activity, alcohol group as acceptor	5.49988294224815	bayes_pls_golite062009
protein kinase activity	5.4586557943719	bayes_pls_golite062009
kinase activity	5.3287080791198	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	4.96052051118534	bayes_pls_golite062009
cyclin-dependent protein kinase activity	4.62392503670521	bayes_pls_golite062009
protein serine/threonine kinase activity	4.46381887831481	bayes_pls_golite062009
transferase activity	3.97138602499442	bayes_pls_golite062009
actin binding	2.91722352767433	bayes_pls_golite062009
binding	2.74863538127007	bayes_pls_golite062009
cytoskeletal protein binding	2.12615078788254	bayes_pls_golite062009
ATP binding	1.97600611746091	bayes_pls_golite062009
adenyl ribonucleotide binding	1.93596671856664	bayes_pls_golite062009
adenyl nucleotide binding	1.90928021591891	bayes_pls_golite062009
actin filament binding	1.75933904320288	bayes_pls_golite062009
purine ribonucleotide binding	1.65732943334212	bayes_pls_golite062009
ribonucleotide binding	1.65726906484847	bayes_pls_golite062009
purine nucleotide binding	1.63763394711025	bayes_pls_golite062009
nucleotide binding	1.63195828048121	bayes_pls_golite062009
transcription regulator activity	1.56748951434625	bayes_pls_golite062009
nucleic acid binding	1.46547714006072	bayes_pls_golite062009
MAP kinase kinase activity	1.42275431028856	bayes_pls_golite062009
protein tyrosine kinase activity	1.3898059094397	bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity	1.38496328649031	bayes_pls_golite062009
DNA binding	1.35333135345112	bayes_pls_golite062009
receptor signaling protein activity	1.27291233344322	bayes_pls_golite062009
protein binding	1.22565748038754	bayes_pls_golite062009
catalytic activity	1.21655087018101	bayes_pls_golite062009
transcription repressor activity	1.14496167267281	bayes_pls_golite062009
tubulin binding	1.13686658158825	bayes_pls_golite062009
transcription factor activity	1.10928254946881	bayes_pls_golite062009
JUN kinase kinase kinase kinase activity	0.926083992524179	bayes_pls_golite062009
MAP kinase activity	0.81943579965027	bayes_pls_golite062009
structural constituent of muscle	0.767275562047313	bayes_pls_golite062009
microtubule binding	0.734274677384472	bayes_pls_golite062009
structural constituent of cytoskeleton	0.612883428421652	bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity	0.48345772948903	bayes_pls_golite062009
enzyme binding	0.46284745266176	bayes_pls_golite062009
kinase binding	0.443916188551908	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.401250804041384	bayes_pls_golite062009
magnesium ion binding	0.393328812780268	bayes_pls_golite062009
MAP kinase kinase kinase activity	0.37115026509016	bayes_pls_golite062009
protein kinase binding	0.285611963740145	bayes_pls_golite062009
signal transducer activity	0.270054246024761	bayes_pls_golite062009
molecular transducer activity	0.270054246024761	bayes_pls_golite062009
myosin binding	0.259936573810332	bayes_pls_golite062009
transporter activity	0.187543377461637	bayes_pls_golite062009
protein complex binding	0.132247221889251	bayes_pls_golite062009
transmembrane receptor protein kinase activity	0.0556163711947139	bayes_pls_golite062009
transmembrane transporter activity	0.0413380592707298	bayes_pls_golite062009
actin-dependent ATPase activity	0.0339299940546054	bayes_pls_golite062009
MAP kinase kinase kinase kinase activity	0.01826424351081	bayes_pls_golite062009
transmembrane receptor activity	0.00652065412910241	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..298]	PSI-BLAST	62.69897	No description for 2j51A was found.
2	View Details	[299..523]	deduced	N/A	No confident structure predictions are available.
3	View Details	[524..652]	deduced	N/A	No confident structure predictions are available.

Protein Overview: nak1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: