YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: lon1

General Information:
Name(s) found: lon1 / SPAC22F3.06c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • Lon protease homolog Lon1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1067 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: misfolded or incompletely synthesized protein catabolic process [ISS]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    serine-type endopeptidase activity [ISS]
    ATP-dependent peptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITRLSGACL RRSGAKRNWP REHLVHRSLL ASFSTTQRVL KCSVGPFRTS NVVFKSKEPK  60
   61 DNKPLDNKND PKKTHNEDES HTNESLPSTD KKKKKDNDDF KQNLKSSSNK TEEKYSATQA 120
  121 SKSKNDEFEL GGEENEDEMP LNGEFNKNVP AKYSVPDVYP QLLALPIARR PLFPGFYKAI 180
  181 VTKNPSVSEA IKELIKKRQP YIGAFLLKDE NTDTDVITNI DQVYPVGVFA QITSIFPAKS 240
  241 GSEPALTAVL YPHRRIRITE LIPPKEDADS AASSDAAELE TDKSSNLSSN GEVKSDLKQD 300
  301 NGKEEPEKEV ESTPSILQNF KVSLVNVENV PNEPFKRQDP VIKAVTSEIM NVFKDIANVS 360
  361 PLFREQIANF SISQTSGNVF DEPAKLADFA AAVSAADHRE LQEVLEATNI GDRLQKALYV 420
  421 LKKELLNAQL QHKINKEIEQ KITQRHKEYL LTEQLKQIKR ELGQELDSKE ALVTEFKKRT 480
  481 ESLSMPDHVK KVFNDELSKF QHLEPMAAEF NITRNYLDWI TQLPWGKRSV ENFDLDHAKE 540
  541 VLDRDHYGLK DVKDRVLELV AVGKLRGTMQ GKIMCLVGPP GVGKTSVGKS IASALNREFF 600
  601 RFSVGGLTDV AEIKGHRRTY IGAMPGKIVQ ALKKVQTENP LILIDEIDKV GKSHQGDPAS 660
  661 ALLELLDSEQ NSAFLDYYMD IPLDVSSVLF VCTANTIDTI PPPLLDRMEV IELSGYVSAE 720
  721 KVNIAKGYLI PQAKAACGLK DANVNISDDA IKGLISYYAH ESGVRNLKKS IEKIFRKTSF 780
  781 SIVKEIDDEL NSKEKSTGKS GKKTSPQSSE DAANKEASSV PLKVPDKVNI EIEEKDLTKY 840
  841 LGPPIYTSQR LYDTTPPGVV MGLGWTPMGG VSMYVETIVK NILSSNSTPS LERTGQLGDV 900
  901 MKESSEISYS FSKSFLSKHF PNNKFFEHAR LHMHCPEGSI SKDGPSAGIT MATSLLSLAL 960
  961 DTPVPATTAM TGELTLTGKI LRIGGLREKT VAAKLSGMKE ILFPKSNLAD WEQLPDYVKE1020
 1021 GLTGVPVAWY DDVFKRVFSN IDAEKCNNLW PNLIKSSSKQ HQISPSH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..843] PSI-BLAST 112.0 Crystal Structure Analysis of ClpB
    2 View Details [844..1067] PSI-BLAST 47.30103 Catalytic domain of E.coli Lon protease

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  3.92757313803074 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.76622182173583 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  3.49412822840068 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.46458392648207 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.411171656739 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.09072076169796 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  2.99135301692379 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.92624263342912 bayes_pls_golite062009
  • hydrolase activity
    		•  2.18454736627863 bayes_pls_golite062009
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.84050240798436 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.81138802583782 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.78927528875848 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.78903889318615 bayes_pls_golite062009
  • helicase activity
    		•  1.40781177352978 bayes_pls_golite062009
  • ATPase activity
    		•  1.18431260772292 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.09000822067541 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.86836375892673 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • motor activity
    		•  0.50661339105747 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.503971340374059 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.384988511775694 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.175442402308287 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.133736530545575 bayes_pls_golite062009
  • DNA binding
    		•  0.111331583742205 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0700789521444061 bayes_pls_golite062009
    2
    Term Confidence Notes
  • mitochondrial heavy strand promoter sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • DNA polymerase binding
    		•  7.07169438832198 bayes_pls_golite062009
  • mitochondrial light strand promoter anti-sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • mitochondrial heavy strand promoter anti-sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • mitochondrial light strand promoter sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • ribonuclease activity
    		•  2.03745175432755 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.38482286547386 bayes_pls_golite062009
  • hydrolase activity
    		•  1.18773479836745 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.16726450662143 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.1604717842042 bayes_pls_golite062009
  • structural molecule activity
    		•  1.14918348313691 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.13566902804592 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.99253423929971 bayes_pls_golite062009
  • binding
    		•  0.923114523007774 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • peptidase activity
    		•  0.46678532223973 bayes_pls_golite062009
  • nuclease activity
    		•  0.315907493060144 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.227419965943609 bayes_pls_golite062009
  • protein binding
    		•  0.214066724623027 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.161393552073973 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.145830549540622 bayes_pls_golite062009
  • exonuclease activity
    		•  0.118186133308559 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.114504249104206 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.0709817198603016 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  6.9430052008157E-5 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle