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Protein Overview: sal3

General Information:
Name(s) found: sal3 / SPCC1840.03 [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • karyopherin Sal3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1095 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed articleLink to PubMed article]
    nuclear membrane [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    nuclear pore [TASLink to PubMed article]
    Biological Process: nucleocytoplasmic transport [TASLink to PubMed article]
    protein import into nucleus [IDALink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    regulation of mitotic cell cycle [IMPLink to PubMed article]
    Molecular Function: GTP binding [NASLink to PubMed article]
    protein transporter activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGFPPEVL SPLLNLVQGL SSPDNTVRND AEKSLSSDWI SQRADLLLNG LAILAYQSED  60
   61 PAVRSFCLVL CRRISFRTLP GDSELEVFSS ISNESKQSLQ SQLLACFVKE SVPTVRNKLC 120
  121 DTIAEIARSI YDCQGEWPEL INVIFNAVNS PDESFRESVF RTITSLPRLL SGQDSAVTPL 180
  181 FTTGLADPSI RVRISAARAY SAVILESKQS TRDQVIPLLP SLMNILPPLQ QDRDSDNLAD 240
  241 CLMAITEIAE VFPKLFKPIF ESVIAFGLGI IKDKELDNSA RQAALELLVC FSEGAPAMCR 300
  301 KSSDYTDQLV LQCLLLMTDV AGDPEDEAEE LQEWLNTDDL DQDESDANHV VAEQAMDRLS 360
  361 RKLGGKTILP PSFTWLPRLI PSQKWSERHA ALMAISSIAE GAEKLMKKEL SRVLDMVLPL 420
  421 LADPHPRVRW AACNAVGQMS TDFAPDMQVK YPSRILEALV PVLESPESRV QAHAAAAMVN 480
  481 FSEEADNKVL EPYLDDILQR LLTLLQSPKR YVQEQAVTTI ATVADAAAKK FEKYFDAIMP 540
  541 LLFNVLQQAD GKEFRTLRGK TMECATLIAL AVGKQRFLPV SQELIQILGN IQMGITDSDD 600
  601 PQASYLISAW GRICRVLGSD FVPFLSSVMP PLLVAATSKP DFTIIDDEVD ESKYSEQDGW 660
  661 EFIPVHGQQV GIRTSTLEDK CTATEMLVCY AAELKADFDP YVNEVLTSVV LPGLKFFFHD 720
  721 GVRSACCKCI PQLLNARILA SNRDPAKVNE LWEPILRKLL DHIQNEPSVE MLADYFECFY 780
  781 QSLEISGLNL SPSSMEALVA AVDLQLKGFI SRVQQREEEA KNGDIDIEED EDMILAVEND 840
  841 QNLLNEINKT FSVVLKIHKT AFCPFWERLL PYMDGFLSGN DTVAKQWALC MMDDLIEFTG 900
  901 PDSWNYKDHF LPYLAEGIQS SEPEIRQAAS YGIGVAAQHG GELYAEICSS ALPALFKMLE 960
  961 LPDARDEEQI YATENICVAI CKICRFCSQR VQDLDKVVTY WINTLPVTHD EDDAPYAYTF1020
 1021 LAELMEQNHV AVASQMPTII TILAETFASG VLRGRTLTRL MEASKVYLAR FPADQVNSVI1080
 1081 ATLSVDNQRA LSAHF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..821] PSI-BLAST 81.69897 No description for 2ot8A was found.
    2 View Details [822..1095] PSI-BLAST 34.39794 Mouse Importin alpha- phosphorylated SV40 CN peptide complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  2.13470398426489 bayes_pls_golite062009
  • RNA binding
    		•  1.91507786651888 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.91487015967262 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.00841167631924 bayes_pls_golite062009
  • signal transducer activity
    		•  0.662662274021266 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.662662274021266 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385452858197632 bayes_pls_golite062009
  • mRNA binding
    		•  0.37278269424461 bayes_pls_golite062009
  • DNA binding
    		•  0.309260217284589 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle