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Protein Overview: tif213

General Information:
Name(s) found: tif213 / SPBC17G9.09 [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • translation initiation factor eIF2 gamma subunit [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 446 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: positive regulation of translational initiation [IC]
    translation [IEA]
    Molecular Function: GTP binding [IEA]
    translation initiation factor activity [IEA]
    GTPase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAENLDISEL SPIHPAIISR QATINIGTIG HVAHGKSTVV KAISGVHTVR FKNELERNIT  60
   61 IKLGYANAKI YKCSNEECPR PGCYRSYSSN KEDHPPCEIC NSPMNLVRHV SFVDCPGHDI 120
  121 LMATMLNGAA VMDAALLLIA GNESCPQPQT SEHLAAIEIM QLKHIIILQN KVDLIRESAA 180
  181 EEHYQSILKF IKGTVAENSP IVPISAQLKY NIDAILEYIV KKIPIPVRDF TTAPRLIVIR 240
  241 SFDVNKPGAE VDDLKGGVAG GSILTGVLRL NDEIEIRPGI VTKDDDGRIR CQPIFSRIIS 300
  301 LFAEHNDLKI AVPGGLIGVG TTVDPTLCRA DRLVGQVLGS KGNLPEVYTE LEINYFLLRR 360
  361 LLGVKSGDKN TTKVQKLAKN EVLMVNIGST STGGRVMMVK ADMAKILLTA PACTEIGEKV 420
  421 ALSRRIEKHW RLIGWAKVVE GKTLKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..446] PSI-BLAST 77.69897 Initiation factor eIF2 gamma subunit, domain II; Initiation factor eIF2 gamma subunit; Initiation factor eIF2 gamma subunit, N-terminal (G) domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation elongation factor activity
    		•  3.34765067410136 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.72462789867829 bayes_pls_golite062009
  • translation initiation factor activity
    		•  2.7201523708414 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51683451033161 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.2817164193758 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • DNA binding
    		•  2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.88455339138556 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.47858140861683 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.29640539057136 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.2935968641033 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.2935353851804 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.29138695385133 bayes_pls_golite062009
  • nucleotide binding
    		•  1.28669586915546 bayes_pls_golite062009
  • helicase activity
    		•  1.16085745407703 bayes_pls_golite062009
  • motor activity
    		•  1.14667913749579 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  1.12431517057397 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.06255786387629 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ATP binding
    		•  0.98146619596929 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.949788783884952 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.931486373329219 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887108427603557 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  0.876296121718575 bayes_pls_golite062009
  • structural molecule activity
    		•  0.86514677273731 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.862685397469217 bayes_pls_golite062009
  • kinase activity
    		•  0.691112783105676 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.60036517876321 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.500462538667228 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.499834566483656 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.249173645231486 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • centromeric DNA binding
    		•  0.120185906020979 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0781650226500197 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0430764033739892 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0364322017534667 bayes_pls_golite062009
  • actin binding
    		•  0.00482938540552702 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.00156323320804219 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.00156323320804219 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.00156323320804219 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle