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Protein Overview: dfp1

General Information:
Name(s) found: dfp1 / SPCC550.13 [Sanger Pombe]
Description(s) found:
Found 25 descriptions.
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  • Hsk1-Dfp1 kinase complex regulatory subunit Dfp1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 545 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    Dbf4-dependent protein kinase complex [IDALink to PubMed article]
    Biological Process: DNA damage checkpoint [IMPLink to PubMed article]
    DNA replication initiation [IMPLink to PubMed article]
    sister chromatid cohesion [IGILink to PubMed article]
    DNA replication checkpoint [IMPLink to PubMed article]
    replication fork protection [TASLink to PubMed article]
    signal transduction [ICLink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    response to DNA damage stimulus [IMPLink to PubMed article]
    regulation of phosphorylation [ICLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPILink to PubMed articleLink to PubMed article]
    protein heterodimerization activity [IPILink to PubMed article]
    protein kinase regulator activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLGRCPLAP RSANIVLPKH DAVSKQKEYR IEEKTNEAQR EEIITWKDNR EDEGEVKTDF  60
   61 EVVNNENIIT TTPKHQTVIT PKSYRKSVKR IKHDAPQNED IPVMKGLAPI NADTESKAES 120
  121 MAAGKVLGSK NSSQKARLQE WKRQYKKAFP HFRFYLDGCD PSVAHRVKKQ IQQLGGHVET 180
  181 FFSGNVTHVA TVRAIQDVSV KYAKQDVITK ARQLNMKIWS MEKLCNRVLK TLMENDQCTT 240
  241 NAPTKQGNDL SYLLYVEKVQ GTNERDLSVP RQDFVHFRGP YLYVHDIANI YKPILLREWQ 300
  301 KPLPDRDVPW PTFRATSIGR CPFVPETKYR LSTSKSLVAK NDQQLLQRQS QEPSLILRAN 360
  361 SMKASLPDIS NTGISGMNTN TTYNTNINNT PQTAISGITQ DTSPSIRTNC HHCLDDGMQA 420
  421 SGIVQSNLTS AAMSNNSAIR SGSAASVPVV TINGRDIAEL KKRIIQQKSG MIGKDYSYKA 480
  481 MLHNTSQRKI RVDAKPGYCE NCREKFDNFE SHIRSSRHRR FAENNDNFKD LDELFALVQR 540
  541 PLRPD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] deduced N/A No confident structure predictions are available.
    2 View Details [115..302] FFAS03 1.31 The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
    3 View Details [303..447] deduced N/A No confident structure predictions are available.
    4 View Details [448..545] FFAS03 1.24 Solution Structure of a Human C2H2-type Zinc Finger Protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA binding
    		•  2.67917489541888 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.54765715003665 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.47222320565852 bayes_pls_golite062009
  • damaged DNA binding
    		•  2.36721002778798 bayes_pls_golite062009
  • binding
    		•  2.35986940498978 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.45436310356985 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.25569054667398 bayes_pls_golite062009
  • protein binding
    		•  1.17425096415314 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.913784026677934 bayes_pls_golite062009
  • transcription activator activity
    		•  0.760275666958713 bayes_pls_golite062009
  • transcription factor binding
    		•  0.698609386505727 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.379584332543036 bayes_pls_golite062009
  • catalytic activity
    		•  0.201193336576136 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0806573268112463 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  4.22191080270855 bayes_pls_golite062009
  • DNA binding
    		•  4.12848717389394 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.04689255235626 bayes_pls_golite062009
  • transcription factor activity
    		•  3.09773531733947 bayes_pls_golite062009
  • binding
    		•  2.99742524370422 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.89448820920797 bayes_pls_golite062009
  • transcription activator activity
    		•  1.89703294042317 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.83572444812059 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.26918933830233 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.26862497534835 bayes_pls_golite062009
  • transcription factor binding
    		•  1.2172880494946 bayes_pls_golite062009
  • chromatin binding
    		•  1.10179307236186 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.04205834745201 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.983886041616211 bayes_pls_golite062009
  • protein binding
    		•  0.952480850696098 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.662695307860787 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.565178169822137 bayes_pls_golite062009
  • catalytic activity
    		•  0.263007611601737 bayes_pls_golite062009
  • histone binding
    		•  0.088089875173164 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle