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View Structure Prediction Details

Protein: dfp1
Organism: Schizosaccharomyces pombe
Length: 545 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dfp1.

Description E-value Query
Range
Subject
Range
gi|4102636 - gi|4102636|gb|AAD01519.1| G1/S regulator [Aspergillus nidulans]
553.0 [0..49] [545..9]
gi|49088112, gi|... - gi|67522645|ref|XP_659383.1| hypothetical protein AN1779.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
489.0 [0..56] [511..1]
gi|28919158, gi|... - gi|32410693|ref|XP_325827.1| hypothetical protein [Neurospora crassa], gi|28919158|gb|EAA28657.1| hy...
gi|85089074 - gi|85089074|ref|XP_957893.1| hypothetical protein [Neurospora crassa OR74A]
479.0 [0..59] [543..13]
gi|45200892, gi|... - gi|45200892|ref|NP_986462.1| AGL205Cp [Ashbya gossypii ATCC 10895], gi|44985662|gb|AAS54286.1| AGL20...
gi|44985662 - gi|44985662|gb|AAS54286.1| AGL205Cp [Ashbya gossypii ATCC 10895]
453.0 [0..82] [539..66]
SPO6_SCHPO - Sporulation-specific protein 6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spo6 PE=3 S...
spo6 - Spo4-Spo6 kinase complex regulatory subunit Spo6
447.0 [0..130] [543..109]
gi|76573716 - gi|76573716|dbj|BAE44800.1| hypothetical protein [Candida albicans]
gi|46438610, gi|... - gi|77022918|ref|XP_888903.1| hypothetical protein CaO19_5166 [Candida albicans SC5314], gi|68478104|...
438.0 [0..57] [539..22]
gi|169769266 - gi|169769266|ref|XP_001819103.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83766961 - gi|83766961|dbj|BAE57101.1| unnamed protein product [Aspergillus oryzae]
437.0 [0..49] [545..9]
gi|66848439, gi|... - gi|70991915|ref|XP_750806.1| G1/S regulator NimO [Aspergillus fumigatus Af293], gi|66848439|gb|EAL88...
431.0 [0..56] [545..1]
gi|115400531, gi... - gi|115400531|ref|XP_001215854.1| hypothetical protein ATEG_06676 [Aspergillus terreus NIH2624], gi|1...
422.0 [0..56] [545..1]
gi|88177606, gi|... - gi|88177606|gb|EAQ85074.1| hypothetical protein CHGG_09088 [Chaetomium globosum CBS 148.51], gi|1162...
404.0 [0..56] [538..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLGRCPLAP RSANIVLPKH DAVSKQKEYR IEEKTNEAQR EEIITWKDNR EDEGEVKTDF  60
   61 EVVNNENIIT TTPKHQTVIT PKSYRKSVKR IKHDAPQNED IPVMKGLAPI NADT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESKAESMAAG KVLGSKNSSQ KARLQEWKRQ YKKAFPHFRF YLDGCDPSVA HRVKKQIQQL  60
   61 GGHVETFFSG NVTHVATVRA IQDVSVKYAK QDVITKARQL NMKIWSMEKL CNRVLKTLME 120
  121 NDQCTTNAPT KQGNDLSYLL YVEKVQGTNE RDLSVPRQDF VHFRGPYLYV HDIANIYKPI 180
  181 LLREWQKP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.31
Match: 1wf6A
Description: The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 2.67917489541888 bayes_pls_golite062009
nucleic acid binding 2.54765715003665 bayes_pls_golite062009
transcription regulator activity 2.47222320565852 bayes_pls_golite062009
damaged DNA binding 2.36721002778798 bayes_pls_golite062009
binding 2.35986940498978 bayes_pls_golite062009
transcription repressor activity 1.45436310356985 bayes_pls_golite062009
sequence-specific DNA binding 1.25569054667398 bayes_pls_golite062009
protein binding 1.17425096415314 bayes_pls_golite062009
telomeric DNA binding 0.913784026677934 bayes_pls_golite062009
transcription activator activity 0.760275666958713 bayes_pls_golite062009
transcription factor binding 0.698609386505727 bayes_pls_golite062009
structure-specific DNA binding 0.379584332543036 bayes_pls_golite062009
catalytic activity 0.201193336576136 bayes_pls_golite062009
double-stranded DNA binding 0.0806573268112463 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [303-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPDRDVPWPT FRATSIGRCP FVPETKYRLS TSKSLVAKND QQLLQRQSQE PSLILRANSM  60
   61 KASLPDISNT GISGMNTNTT YNTNINNTPQ TAISGITQDT SPSIRTNCHH CLDDGMQASG 120
  121 IVQSNLTSAA MSNNSAIRSG SAASV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [448-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVVTINGRDI AELKKRIIQQ KSGMIGKDYS YKAMLHNTSQ RKIRVDAKPG YCENCREKFD  60
   61 NFESHIRSSR HRRFAENNDN FKDLDELFAL VQRPLRPD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.24
Match: 1zr9A
Description: Solution Structure of a Human C2H2-type Zinc Finger Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.22191080270855 bayes_pls_golite062009
DNA binding 4.12848717389394 bayes_pls_golite062009
nucleic acid binding 4.04689255235626 bayes_pls_golite062009
transcription factor activity 3.09773531733947 bayes_pls_golite062009
binding 2.99742524370422 bayes_pls_golite062009
transcription repressor activity 2.89448820920797 bayes_pls_golite062009
transcription activator activity 1.89703294042317 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.83572444812059 bayes_pls_golite062009
structure-specific DNA binding 1.26918933830233 bayes_pls_golite062009
sequence-specific DNA binding 1.26862497534835 bayes_pls_golite062009
transcription factor binding 1.2172880494946 bayes_pls_golite062009
chromatin binding 1.10179307236186 bayes_pls_golite062009
transcription corepressor activity 1.04205834745201 bayes_pls_golite062009
double-stranded DNA binding 0.983886041616211 bayes_pls_golite062009
protein binding 0.952480850696098 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.662695307860787 bayes_pls_golite062009
transcription cofactor activity 0.565178169822137 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009
histone binding 0.088089875173164 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle