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View Structure Prediction Details

Protein: dfp1
Organism: Schizosaccharomyces pombe
Length: 545 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dfp1.

Description E-value Query
Range
Subject
Range
gi|4102636 - gi|4102636|gb|AAD01519.1| G1/S regulator [Aspergillus nidulans]
553.0 [0..49] [545..9]
gi|49088112, gi|... - gi|67522645|ref|XP_659383.1| hypothetical protein AN1779.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
489.0 [0..56] [511..1]
gi|28919158, gi|... - gi|32410693|ref|XP_325827.1| hypothetical protein [Neurospora crassa], gi|28919158|gb|EAA28657.1| hy...
gi|85089074 - gi|85089074|ref|XP_957893.1| hypothetical protein [Neurospora crassa OR74A]
479.0 [0..59] [543..13]
gi|45200892, gi|... - gi|45200892|ref|NP_986462.1| AGL205Cp [Ashbya gossypii ATCC 10895], gi|44985662|gb|AAS54286.1| AGL20...
gi|44985662 - gi|44985662|gb|AAS54286.1| AGL205Cp [Ashbya gossypii ATCC 10895]
453.0 [0..82] [539..66]
SPO6_SCHPO - Sporulation-specific protein 6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spo6 PE=3 S...
spo6 - Spo4-Spo6 kinase complex regulatory subunit Spo6
447.0 [0..130] [543..109]
gi|76573716 - gi|76573716|dbj|BAE44800.1| hypothetical protein [Candida albicans]
gi|46438610, gi|... - gi|77022918|ref|XP_888903.1| hypothetical protein CaO19_5166 [Candida albicans SC5314], gi|68478104|...
438.0 [0..57] [539..22]
gi|169769266 - gi|169769266|ref|XP_001819103.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83766961 - gi|83766961|dbj|BAE57101.1| unnamed protein product [Aspergillus oryzae]
437.0 [0..49] [545..9]
gi|66848439, gi|... - gi|70991915|ref|XP_750806.1| G1/S regulator NimO [Aspergillus fumigatus Af293], gi|66848439|gb|EAL88...
431.0 [0..56] [545..1]
gi|115400531, gi... - gi|115400531|ref|XP_001215854.1| hypothetical protein ATEG_06676 [Aspergillus terreus NIH2624], gi|1...
422.0 [0..56] [545..1]
gi|88177606, gi|... - gi|88177606|gb|EAQ85074.1| hypothetical protein CHGG_09088 [Chaetomium globosum CBS 148.51], gi|1162...
404.0 [0..56] [538..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLGRCPLAP RSANIVLPKH DAVSKQKEYR IEEKTNEAQR EEIITWKDNR EDEGEVKTDF  60
   61 EVVNNENIIT TTPKHQTVIT PKSYRKSVKR IKHDAPQNED IPVMKGLAPI NADT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.267 d.1.1 Microbial ribonucleases
View Download 0.213 c.52.2 tRNA splicing endonuclease, C-terminal domain
View Download 0.248 b.34.11 GW domain
View Download 0.205 d.17.2 Copper amine oxidase, domains 1 and 2

Predicted Domain #2
Region A:
Residues: [115-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESKAESMAAG KVLGSKNSSQ KARLQEWKRQ YKKAFPHFRF YLDGCDPSVA HRVKKQIQQL  60
   61 GGHVETFFSG NVTHVATVRA IQDVSVKYAK QDVITKARQL NMKIWSMEKL CNRVLKTLME 120
  121 NDQCTTNAPT KQGNDLSYLL YVEKVQGTNE RDLSVPRQDF VHFRGPYLYV HDIANIYKPI 180
  181 LLREWQKP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.31
Match: 1wf6A
Description: The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 2.67917489541888 bayes_pls_golite062009
nucleic acid binding 2.54765715003665 bayes_pls_golite062009
transcription regulator activity 2.47222320565852 bayes_pls_golite062009
damaged DNA binding 2.36721002778798 bayes_pls_golite062009
binding 2.35986940498978 bayes_pls_golite062009
transcription repressor activity 1.45436310356985 bayes_pls_golite062009
sequence-specific DNA binding 1.25569054667398 bayes_pls_golite062009
protein binding 1.17425096415314 bayes_pls_golite062009
telomeric DNA binding 0.913784026677934 bayes_pls_golite062009
transcription activator activity 0.760275666958713 bayes_pls_golite062009
transcription factor binding 0.698609386505727 bayes_pls_golite062009
structure-specific DNA binding 0.379584332543036 bayes_pls_golite062009
catalytic activity 0.201193336576136 bayes_pls_golite062009
double-stranded DNA binding 0.0806573268112463 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [303-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPDRDVPWPT FRATSIGRCP FVPETKYRLS TSKSLVAKND QQLLQRQSQE PSLILRANSM  60
   61 KASLPDISNT GISGMNTNTT YNTNINNTPQ TAISGITQDT SPSIRTNCHH CLDDGMQASG 120
  121 IVQSNLTSAA MSNNSAIRSG SAASV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [448-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVVTINGRDI AELKKRIIQQ KSGMIGKDYS YKAMLHNTSQ RKIRVDAKPG YCENCREKFD  60
   61 NFESHIRSSR HRRFAENNDN FKDLDELFAL VQRPLRPD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.24
Match: 1zr9A
Description: Solution Structure of a Human C2H2-type Zinc Finger Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.22191080270855 bayes_pls_golite062009
DNA binding 4.12848717389394 bayes_pls_golite062009
nucleic acid binding 4.04689255235626 bayes_pls_golite062009
transcription factor activity 3.09773531733947 bayes_pls_golite062009
binding 2.99742524370422 bayes_pls_golite062009
transcription repressor activity 2.89448820920797 bayes_pls_golite062009
transcription activator activity 1.89703294042317 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.83572444812059 bayes_pls_golite062009
structure-specific DNA binding 1.26918933830233 bayes_pls_golite062009
sequence-specific DNA binding 1.26862497534835 bayes_pls_golite062009
transcription factor binding 1.2172880494946 bayes_pls_golite062009
chromatin binding 1.10179307236186 bayes_pls_golite062009
transcription corepressor activity 1.04205834745201 bayes_pls_golite062009
double-stranded DNA binding 0.983886041616211 bayes_pls_golite062009
protein binding 0.952480850696098 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.662695307860787 bayes_pls_golite062009
transcription cofactor activity 0.565178169822137 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009
histone binding 0.088089875173164 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle