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Protein Overview: cbh2

General Information:
Name(s) found: cbh2 / SPBC14F5.12c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • centromere binding protein Cbh2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 514 amino acids

    Gene Ontology:
    Cellular Component: condensed nuclear chromosome, centromeric region [NASLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: chromatin silencing at centromere [TASLink to PubMed article]
    histone modification [TASLink to PubMed article]
    chromosome segregation [TASLink to PubMed article]
    Molecular Function: protein dimerization activity [NASLink to PubMed article]
    centromeric DNA binding [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPLRRQALT LAEKKAIRKH YFESATKPSQ QELISWFEEH FHKKLAQSTV SSILSSKNEF  60
   61 LDNLDAENSQ IRRNRQGKYP ILENALIDWQ TRLQKQDGAI TGNAIKKSAA ELWRRIPEYS 120
  121 ELPIPEFSNG WLEKFKKRCL KHGLKLQGES TSVNQGTYEE NMVQIQELIS LFDPKDIFNM 180
  181 DETGLCWKLI PNQSPASERV KGITRDKARV TVTICCNATG SEKAPLWVIG YAKSPRAFRQ 240
  241 ANAHPDSMDF HWRYNGTARM TTSIMEEWLR WFDDLMKGRK VLLILDKFVA HECALENIRN 300
  301 SERKLVNTTV VFLPVNSTEI YHPCGQEIVY AFKSYYRKYW LNYMLEEIRL GKNPSKTMNV 360
  361 LKAVRWMIRS WNVDFEPSII YNCFLRSGLF QNQQPLTGPS PETIRIAVNL QELIGKYLGD 420
  421 KDIFQIENFI NPIEENSADT NDDIVNQVAA QFLDEREFET DEEEEESQYL LSTKDAINAI 480
  481 NTLLNFQEQS EDGNVLFTRT LLQFQKVLES RSIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] PSI-BLAST 25.69897 Ars-binding protein 1, ABP1
    2 View Details [157..407] FFAS03 1.42 No description for 2f7tA was found.
    3 View Details [408..514] MSA 3.148996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.55154985983449 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.49423102874486 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.24134446233807 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • centromeric DNA binding
    		•  1.13545283098583 bayes_pls_golite062009
  • chromatin binding
    		•  1.04132983826241 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.922310816608639 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.922310816608639 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.666799964992178 bayes_pls_golite062009
  • actin binding
    		•  0.6102552688489 bayes_pls_golite062009
  • histone binding
    		•  0.557787598121402 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.284650049512347 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.187022204923867 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.141400887946529 bayes_pls_golite062009
  • protein deacetylase activity
    		•  0.13314897698019 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.105174598157041 bayes_pls_golite062009
  • histone deacetylase activity
    		•  0.0878521297613482 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.00788099347317628 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle