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View Structure Prediction Details

Protein: cbh2
Organism: Schizosaccharomyces pombe
Length: 514 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cbh2.

Description E-value Query
Range
Subject
Range
ABP1_SCHPO - ARS-binding protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=abp1 PE=1 SV=2
cbp1 - CENP-B homolog
411.0 [0..1] [511..1]
gi|1072102 - gi|1072102|gb|AAB01537.1| ARS binding protein 1
411.0 [0..1] [511..1]
gi|34860486, gi|... - gi|34860486|ref|XP_235818.2| PREDICTED: similar to jerky homolog-like [Rattus norvegicus], gi|157822...
410.0 [0..2] [508..3]
gi|67903460, gi|... - gi|67903460|ref|XP_681986.1| hypothetical protein AN8717.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
408.0 [0..1] [513..1]
JERKL_MOUSE - Jerky protein homolog-like OS=Mus musculus GN=Jrkl PE=2 SV=1
405.0 [0..2] [508..3]
TIGD2 - tigger transposable element derived 2
403.0 [0..1] [508..2]
gi|114596396 - gi|114596396|ref|XP_001153845.1| PREDICTED: tigger transposable element derived 4 [Pan troglodytes]
402.0 [0..4] [512..16]

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Predicted Domain #1
Region A:
Residues: [1-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPLRRQALT LAEKKAIRKH YFESATKPSQ QELISWFEEH FHKKLAQSTV SSILSSKNEF  60
   61 LDNLDAENSQ IRRNRQGKYP ILENALIDWQ TRLQKQDGAI TGNAIKKSAA ELWRRIPEYS 120
  121 ELPIPEFSNG WLEKFKKRCL KHGLKLQGES TSVNQG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1iufA
Description: Ars-binding protein 1, ABP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
transcription repressor activity 3.55154985983449 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription corepressor activity 1.49423102874486 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
cytoskeletal protein binding 1.24134446233807 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
centromeric DNA binding 1.13545283098583 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.922310816608639 bayes_pls_golite062009
histone acetyltransferase activity 0.922310816608639 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
DNA-dependent ATPase activity 0.666799964992178 bayes_pls_golite062009
actin binding 0.6102552688489 bayes_pls_golite062009
histone binding 0.557787598121402 bayes_pls_golite062009
telomeric DNA binding 0.284650049512347 bayes_pls_golite062009
DNA helicase activity 0.187022204923867 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.141400887946529 bayes_pls_golite062009
protein deacetylase activity 0.13314897698019 bayes_pls_golite062009
structure-specific DNA binding 0.105174598157041 bayes_pls_golite062009
histone deacetylase activity 0.0878521297613482 bayes_pls_golite062009
nucleotidyltransferase activity 0.00788099347317628 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [157-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TYEENMVQIQ ELISLFDPKD IFNMDETGLC WKLIPNQSPA SERVKGITRD KARVTVTICC  60
   61 NATGSEKAPL WVIGYAKSPR AFRQANAHPD SMDFHWRYNG TARMTTSIME EWLRWFDDLM 120
  121 KGRKVLLILD KFVAHECALE NIRNSERKLV NTTVVFLPVN STEIYHPCGQ EIVYAFKSYY 180
  181 RKYWLNYMLE EIRLGKNPSK TMNVLKAVRW MIRSWNVDFE PSIIYNCFLR SGLFQNQQPL 240
  241 TGPSPETIRI A

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.42
Match: 2f7tA
Description: No description for 2f7tA was found.

Predicted Domain #3
Region A:
Residues: [408-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNLQELIGKY LGDKDIFQIE NFINPIEENS ADTNDDIVNQ VAAQFLDERE FETDEEEEES  60
   61 QYLLSTKDAI NAINTLLNFQ EQSEDGNVLF TRTLLQFQKV LESRSIV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle