Protein Overview: if-PF, if-PD, if-PB

General Information:
Name(s) found:	if-PF / FBpp0290568 [FlyBase] if-PD / FBpp0290567 [FlyBase] if-PB / FBpp0074131 [FlyBase]
Description(s) found: Found 37 descriptions. SHOW ALL	The gene inflated is referred to in FlyBase by the symbol Dmel\if (CG9623, FBgn0001250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16646222..16677467. It has the cytological map location 15A5-15A7. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; axon guidance; axonal defasciculation; myofibril assembly; cell adhesion; imaginal disc-derived wing morphogenesis; maintenance of epithelial integrity, open tracheal system; maintenance of protein location; muscle attachment; salivary gland morphogenesis. 80 alleles are reported. The phenotypes of these alleles are annotated with 46 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; primordium; adult segment; embryonic nervous system; larval abdominal segment 5; adult mesothoracic segment; nervous system; larval abdominal segment; peripheral nervous system. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene inflated is referred to in FlyBase by the symbol Dmel\if (CG9623, FBgn0001250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16646222..16677467. It has the cytological map location 15A5-15A7. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; axon guidance; axonal defasciculation; myofibril assembly; cell adhesion; imaginal disc-derived wing morphogenesis; maintenance of epithelial integrity, open tracheal system; maintenance of protein location; muscle attachment; salivary gland morphogenesis. 80 alleles are reported. The phenotypes of these alleles are annotated with 46 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; primordium; adult segment; embryonic nervous system; larval abdominal segment 5; adult mesothoracic segment; nervous system; larval abdominal segment; peripheral nervous system. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene inflated is referred to in FlyBase by the symbol Dmel\if (CG9623, FBgn0001250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16646222..16677467. It has the cytological map location 15A5-15A7. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; axon guidance; axonal defasciculation; myofibril assembly; cell adhesion; imaginal disc-derived wing morphogenesis; maintenance of epithelial integrity, open tracheal system; maintenance of protein location; muscle attachment; salivary gland morphogenesis. 80 alleles are reported. The phenotypes of these alleles are annotated with 46 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; primordium; adult segment; embryonic nervous system; larval abdominal segment 5; adult mesothoracic segment; nervous system; larval abdominal segment; peripheral nervous system. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1396 amino acids
Gene Ontology:
Cellular Component:	contractile fiber [IDA] integrin complex [IEA][ISS][NAS][TAS]
Biological Process:	cell-cell adhesion [TAS] cell-matrix adhesion [ISS] regulation of cell shape [IMP] midgut development [TAS] imaginal disc-derived wing morphogenesis [IEP][IMP][TAS] heterophilic cell-cell adhesion [TAS] axon guidance [IMP] cell adhesion [IDA][IMP] salivary gland development [TAS] apposition of dorsal and ventral imaginal disc-derived wing surfaces [NAS] maintenance of epithelial integrity, open tracheal system [IGI] axonal defasciculation [IMP] tracheal outgrowth, open tracheal system [TAS] salivary gland morphogenesis [IGI] myofibril assembly [IMP] maintenance of protein location [IMP] epithelial cell migration, open tracheal system [TAS] cell migration [TAS] muscle attachment [IGI][IMP]
Molecular Function:	protein binding [TAS] cell adhesion molecule binding [IDA][ISS] receptor activity [IDA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGDSIHRRR MALHCPITSL ILLLIAMSAH GYNIDLPSYV RFRQSSNSMF GFSIAMHKGR  60
   61 SGFYGNQNNV SLIVGAPKFD TSRYQQGVTE AGGVFKCSLN DDDCKLVPFD SKGNNRNVDK 120
  121 EVVDRKSYQW LGATVATGRD SDLVVACAPR YVFHTMTPSR AFRIDPVGTC FTSHNFEEFY 180
  181 EVSPCRTNNW GYHRQGSCQA GFSAAINGNG SRLFIGAPGS WYWQGQTYSI PPDAKFPFKP 240
  241 PLYQPFGTGG MASSHDVTRP ENQVFSTSES ASVNDDSYLG YSMVTGDFDG DRSEDVAIGM 300
  301 PRGGNLVGRI VVNRWNMANI FNITGRQIGE YFGYSLATSD VDGDGLDDLL IGAPMYTDPD 360
  361 NVEGKYDVGR VYILLQGGPT EEKRWTTEHI RDGYHSKGRF GLALTTLGDV NGDGYGDFAV 420
  421 GAPYDGPEGR GVVYIFHGSP MGPLAKPSQI IKSEQLVEGA PYPRTFGFAL SGGLDMDGNT 480
  481 YPDLAVGAYS SDQVFIFKSR PVAAVNAETS FASNSKLISL DDRSCQLVRD HKKVPCMLLT 540
  541 TCWSYTGRYL PEQLDFDVSW LLDAKKLLNP RMFFLRDEGK NIRNQTIRLN YGQKYCLNET 600
  601 VYLLDKVQDK LTPLEVEARY NLRSSRPLDP MVRHRRSILE PVIDQNREIV LRDAINIQKN 660
  661 CGPDNICEPD LKLKVSTVDK YLFGSPEPLV IEVFISNTNE DAFEAAFYMV TPPDLQFRKL 720
  721 QQLGEKKDTP ITCSPPTPEN NHTLKCDIGN PLESGKIAHF KISLVPEEKY GSSSSYDFYW 780
  781 EANSTNLEKP GSEYDNKIRQ SVGIWVDTDL DIKGTSLPDY QLYKADDYKE LENATKEDDI 840
  841 GPQVVHIYEI RNNRPSIIEE AEVFIHLPYE TIVGDPLMYL LNQPETGGKI QCDDVAFNEY 900
  901 NLLLDEKLVK KSYLQAQGAI WNSAQVSGQS SSSSSSGGAS VHIEKARGEG FVRGVLVSNS 960
  961 TDAGDKLSPK QVEQRRQEDT LEALGDASFV HRDRASQAVQ EPQVNQTSFT TYSTSSSSSG1020
 1021 SGAPSAQLRG HSTQGHIQMA GPVQHTSSSS SSNYRSWPAQ QQQQHQQLLL AGSGGSGLGS1080
 1081 PVTFNDKSQF GGRNNNFHTG TLDLGTLNRG NVDNELYRSQ GQYQNPSQSL GQSQGQFQAN1140
 1141 ANQGHYQGQN QAQFQARNPG FQGQTSYQGQ TQYSGQPGGY QTHHVTYSSG SKPYYGRENE1200
 1201 DFYDEDNLQQ ATPGHWSSSS SSSSSSGTRR LRRSNDKDGA TEKPLQIDLN SPCQSARCKS1260
 1261 IRCVVTNLGT EDGDAAFVAI RARMVAKTME KLASNVPLNV STLAVANVTL LPFIGAPKDA1320
 1321 IVKTHEIFYK AEPEPLQVPD VVPLWVVVLA ACAGALIFLL LVWLLYKCGF FNRNRPTDHS1380
 1381 QERQPLRNGY HGDEHL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..1021]	PSI-BLAST	1000.0	Thigh, calf-1 and calf-2 domains of integrin alpha; Integrin alpha N-terminal domain
2	View Details	[1022..1238]	PSI-BLAST	3.522879	Sec24
3	View Details	[1239..1396]	FFAS03	0.977	Class I MHC, alpha-3 domain; Class I MHC, alpha-1 and alpha-2 domains

Protein Overview: if-PF, if-PD, if-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: